4a0g: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
Line 1: Line 1:


==Structure of bifunctional DAPA aminotransferase-DTB synthetase from Arabidopsis thaliana in its apo form.==
==Structure of bifunctional DAPA aminotransferase-DTB synthetase from Arabidopsis thaliana in its apo form.==
<StructureSection load='4a0g' size='340' side='right' caption='[[4a0g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4a0g' size='340' side='right'caption='[[4a0g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4a0g]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A0G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A0G FirstGlance]. <br>
<table><tr><td colspan='2'>[[4a0g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A0G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A0G FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4a0f|4a0f]], [[4a0h|4a0h]], [[4a0r|4a0r]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4a0f|4a0f]], [[4a0h|4a0h]], [[4a0r|4a0r]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a0g OCA], [http://pdbe.org/4a0g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a0g RCSB], [http://www.ebi.ac.uk/pdbsum/4a0g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a0g ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a0g OCA], [https://pdbe.org/4a0g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a0g RCSB], [https://www.ebi.ac.uk/pdbsum/4a0g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a0g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BIODA_ARATH BIODA_ARATH]] Bifunctional enzyme that catalyzes two different reactions involved in the biotin biosynthesis.  Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.  Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor.  
[[https://www.uniprot.org/uniprot/BIODA_ARATH BIODA_ARATH]] Bifunctional enzyme that catalyzes two different reactions involved in the biotin biosynthesis.  Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.  Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor.  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 27: Line 27:
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arath]]
[[Category: Large Structures]]
[[Category: Alban, C]]
[[Category: Alban, C]]
[[Category: Cobessi, D]]
[[Category: Cobessi, D]]
Retrieved from "https://proteopedia.org/4a0g"