2cib: Difference between revisions

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[[Image:2cib.~~gif~~|left|200px]]<br />

[[Image:2cib.jpg|left|200px]]<br /><applet load="2cib" size="450" color="white" frame="true" align="right" spinBox="true"

<applet load="2cib" size="450" color="white" frame="true" align="right" spinBox="true"

caption="2cib, resolution 1.50Å" />

'''HIGH THROUGHPUT SCREENING AND X-RAY CRYSTALLOGRAPHY ASSISTED EVALUATION OF SMALL MOLECULE SCAFFOLDS FOR CYP51 INHIBITORS'''<br />

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==About this Structure==

2CIB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with HEM and CM6 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70] ~~Structure known Active~~ Sites: AC1 and AC2. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CIB OCA].

2CIB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with HEM and CM6 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70] Known structural/functional Sites: <scene name='pdbsite=AC1:Hem Binding Site For Chain A'>AC1</scene> and <scene name='pdbsite=AC2:Cm6 Binding Site For Chain A'>AC2</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CIB OCA].

==Reference==

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[[Category: sterol biosynthesis]]

''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on ~~Mon Nov 5~~ 18:09:54 2007''

''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 19:23:52 2007''

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@@ Line 1: / Line 1: @@
-[[Image:2cib.gif|left|200px]]<br />
+[[Image:2cib.jpg|left|200px]]<br /><applet load="2cib" size="450" color="white" frame="true" align="right" spinBox="true"
-<applet load="2cib" size="450" color="white" frame="true" align="right" spinBox="true"
 caption="2cib, resolution 1.50&Aring;" />
 '''HIGH THROUGHPUT SCREENING AND X-RAY CRYSTALLOGRAPHY ASSISTED EVALUATION OF SMALL MOLECULE SCAFFOLDS FOR CYP51 INHIBITORS'''<br />
@@ Line 8: / Line 7: @@
 ==About this Structure==
-CIB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with HEM and CM6 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70] Structure known Active Sites: AC1 and AC2. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CIB OCA].
+CIB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with HEM and CM6 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70] Known structural/functional Sites: <scene name='pdbsite=AC1:Hem Binding Site For Chain A'>AC1</scene> and <scene name='pdbsite=AC2:Cm6 Binding Site For Chain A'>AC2</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CIB OCA].
 ==Reference==
@@ Line 32: / Line 31: @@
 [[Category: sterol biosynthesis]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov  5 18:09:54 2007''
+''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 19:23:52 2007''