6odl: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6odl is ~~ON HOLD until Paper Publication~~

==Crystal structure of GluN2A agonist binding domain with 4-butyl-(S)-CCG-IV==

~~Authors~~: ~~Mou~~, T.C., ~~Clausen~~, R.P., ~~Sprang, S~~.R., ~~Hansen, K~~.B.

== Structural highlights ==

<table><tr><td colspan='2'>[[6odl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ODL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ODL FirstGlance]. <br>

~~Description~~: ~~Crystal structure~~ of ~~GluN2A agonist binding domain with 4~~-~~butyl~~-~~(S)-CCG-IV~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=M7V:(1S,2R)-2-[(S)-amino(carboxy)methyl]-1-butylcyclopropane-1-carboxylic+acid'>M7V</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6odl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6odl OCA], [http://pdbe.org/6odl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6odl RCSB], [http://www.ebi.ac.uk/pdbsum/6odl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6odl ProSAT]</span></td></tr>

[[Category: ~~Mou~~, ~~T.C~~]]

</table>

[[Category: Hansen, K.B]]

== Function ==

[[Category: Sprang, S.R]]

[[http://www.uniprot.org/uniprot/NMDE1_RAT NMDE1_RAT]] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.

[[Category: ~~Clausen, R.P~~]]

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Clausen, R P]]

[[Category: Hansen, K B]]

[[Category: Mou, T C]]

[[Category: Sprang, S R]]

[[Category: Antagonist]]

[[Category: Nmda receptor]]

[[Category: Receptor]]

[[Category: Transport protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6odl is ON HOLD  until Paper Publication
+==Crystal structure of GluN2A agonist binding domain with 4-butyl-(S)-CCG-IV==
+<StructureSection load='6odl' size='340' side='right'caption='[[6odl]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-Authors: Mou, T.C., Clausen, R.P., Sprang, S.R., Hansen, K.B.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6odl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ODL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ODL FirstGlance]. <br>
-Description: Crystal structure of GluN2A agonist binding domain with 4-butyl-(S)-CCG-IV
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=M7V:(1S,2R)-2-[(S)-amino(carboxy)methyl]-1-butylcyclopropane-1-carboxylic+acid'>M7V</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6odl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6odl OCA], [http://pdbe.org/6odl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6odl RCSB], [http://www.ebi.ac.uk/pdbsum/6odl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6odl ProSAT]</span></td></tr>
-[[Category: Mou, T.C]]
+</table>
-[[Category: Hansen, K.B]]
+== Function ==
-[[Category: Sprang, S.R]]
+[[http://www.uniprot.org/uniprot/NMDE1_RAT NMDE1_RAT]] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
-[[Category: Clausen, R.P]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Clausen, R P]]
+[[Category: Hansen, K B]]
+[[Category: Mou, T C]]
+[[Category: Sprang, S R]]
+[[Category: Antagonist]]
+[[Category: Nmda receptor]]
+[[Category: Receptor]]
+[[Category: Transport protein]]