4iyo: Difference between revisions

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<StructureSection load='4iyo' size='340' side='right'caption='[[4iyo]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4iyo' size='340' side='right'caption='[[4iyo]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4iyo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Xanor Xanor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IYO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IYO FirstGlance]. <br>
<table><tr><td colspan='2'>[[4iyo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_oryzae_pv._oryzae_KACC_10331 Xanthomonas oryzae pv. oryzae KACC 10331]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IYO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0JO:2-{[(E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE]AMINO}PROP-2-ENOIC+ACID'>0JO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAK:AMINO-ACRYLATE'>NAK</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene>, <scene name='pdbligand=SER:SERINE'>SER</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0JO:2-{[(E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE]AMINO}PROP-2-ENOIC+ACID'>0JO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=NAK:AMINO-ACRYLATE'>NAK</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene>, <scene name='pdbligand=SER:SERINE'>SER</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iyo OCA], [https://pdbe.org/4iyo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iyo RCSB], [https://www.ebi.ac.uk/pdbsum/4iyo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iyo ProSAT]</span></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ixs|4ixs]], [[4ixz|4ixz]], [[4iy7|4iy7]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">metB, XOCGL, XOO0778 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=291331 XANOR])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cystathionine_gamma-lyase Cystathionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.1 4.4.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iyo OCA], [http://pdbe.org/4iyo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4iyo RCSB], [http://www.ebi.ac.uk/pdbsum/4iyo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4iyo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5H4T8_XANOR Q5H4T8_XANOR]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cystathionine gamma-lyase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Xanor]]
[[Category: Xanthomonas oryzae pv. oryzae KACC 10331]]
[[Category: Kang, L W]]
[[Category: Kang LW]]
[[Category: Kim, J K]]
[[Category: Kim JK]]
[[Category: Ngo, H P.T]]
[[Category: Ngo HPT]]
[[Category: Cys-met metabolism plp dependent enzyme]]
[[Category: Cystathionine gamma lyase]]
[[Category: Iminopropionate]]
[[Category: Lyase]]
[[Category: Plp binding]]
[[Category: Plp dependent enzyme]]
[[Category: Serine]]
[[Category: Xocgl]]

Revision as of 21:20, 16 November 2022

Crystal structure of cystathionine gamma lyase from Xanthomonas oryzae pv. oryzae (XometC) in complex with E-site serine, A-site serine, A-site external aldimine structure with aminoacrylate and A-site iminopropionate intermediates

4iyo, resolution 1.80Å

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