4k21: Difference between revisions

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<StructureSection load='4k21' size='340' side='right'caption='[[4k21]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='4k21' size='340' side='right'caption='[[4k21]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4k21]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_boliviana Canavalia boliviana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K21 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4k21]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_boliviana Canavalia boliviana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K21 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k1y|4k1y]], [[4k1z|4k1z]], [[4k20|4k20]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k21 OCA], [https://pdbe.org/4k21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k21 RCSB], [https://www.ebi.ac.uk/pdbsum/4k21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k21 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k21 OCA], [http://pdbe.org/4k21 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k21 RCSB], [http://www.ebi.ac.uk/pdbsum/4k21 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k21 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LECA_CANBL LECA_CANBL] D-mannose/D-glucose-binding lectin (PubMed:24865454). Has anti-inflammatory activity in animal models when applied intravenously (PubMed:24865454). Has antinociceptive activity in mice when applied intravenously (PubMed:19705102).<ref>PMID:19705102</ref> <ref>PMID:24865454</ref>
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Canavalia boliviana]]
[[Category: Canavalia boliviana]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bezerra, G A]]
[[Category: Bezerra GA]]
[[Category: Cavada, B S]]
[[Category: Cavada BS]]
[[Category: Delatorre, P]]
[[Category: Delatorre P]]
[[Category: Gruber, K]]
[[Category: Gruber K]]
[[Category: Moura, T R]]
[[Category: Moura TR]]
[[Category: Nagano, C S]]
[[Category: Nagano CS]]
[[Category: Rocha, B A.M]]
[[Category: Rocha BAM]]
[[Category: Viertlmayr, R]]
[[Category: Viertlmayr R]]
[[Category: Binding site]]
[[Category: Carbohydrate binding]]
[[Category: Dimannoside]]
[[Category: Diocleinae lectin]]
[[Category: Jelly roll]]
[[Category: Mannose binding protein]]
[[Category: Oligomerization]]