6jmv: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6jmv is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal structure of the GluK3 ligand binding domain complex with SYM and zinc==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6jmv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JMV OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JMV FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SYM:2S,4R-4-METHYLGLUTAMATE'>SYM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[6jfy|6jfy]], [[6jfz|6jfz]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jmv OCA], [http://pdbe.org/6jmv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jmv RCSB], [http://www.ebi.ac.uk/pdbsum/6jmv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jmv ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/GRIK3_RAT GRIK3_RAT]] Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.<ref>PMID:21907808</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Kumar, J]]

[[Category: Kumari, J]]

[[Category: Glutamate receptor]]

[[Category: Kainate]]

[[Category: Membrane protein]]

[[Category: Sym]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6jmv is ON HOLD  until Paper Publication
+==Crystal structure of the GluK3 ligand binding domain complex with SYM and zinc==
+<StructureSection load='6jmv' size='340' side='right'caption='[[6jmv]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6jmv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JMV FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SYM:2S,4R-4-METHYLGLUTAMATE'>SYM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6jfy|6jfy]], [[6jfz|6jfz]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jmv OCA], [http://pdbe.org/6jmv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jmv RCSB], [http://www.ebi.ac.uk/pdbsum/6jmv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jmv ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/GRIK3_RAT GRIK3_RAT]] Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.<ref>PMID:21907808</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Kumar, J]]
+[[Category: Kumari, J]]
+[[Category: Glutamate receptor]]
+[[Category: Kainate]]
+[[Category: Membrane protein]]
+[[Category: Sym]]