6r3f: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 6r3f is ON HOLD until Paper Publication~~

==Aspergillus niger ferulic acid decarboxylase (Fdc) E282Q variant in complex with the covalent adduct formed between prFMN cofactor and cinnamic acid (Int2)==

~~Authors: Bailey, S.S., Leys, D.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[6r3f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R3F OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6R3F FirstGlance].

~~Description:~~ Aspergillus niger ferulic acid decarboxylase (Fdc) E282Q variant in complex with the covalent adduct formed between prFMN cofactor and cinnamic acid (Int2)

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=JQK:[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-[(16~{R})-11,12,14,14-tetramethyl-5-oxidanyl-3-oxidanylidene-16-(2-phenylethyl)-1,4,6,8-tetrazatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-2(7),5,9(17),10,12-pentaen-8-yl]pentyl]+dihydrogen+phosphate'>JQK</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Phenacrylate_decarboxylase Phenacrylate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.102 4.1.1.102] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6r3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r3f OCA], [http://pdbe.org/6r3f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r3f RCSB], [http://www.ebi.ac.uk/pdbsum/6r3f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r3f ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/FDC1_ASPNC FDC1_ASPNC]] Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.[HAMAP-Rule:MF_03196]<ref>PMID:26083754</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Phenacrylate decarboxylase]]

[[Category: Bailey, S S]]

[[Category: Leys, D]]

[[Category: ~~Bailey, S.S~~]]

[[Category: Lyase]]

[[Category: Prfmn binding]]

[[Category: Ubid]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6r3f is ON HOLD  until Paper Publication
+==Aspergillus niger ferulic acid decarboxylase (Fdc) E282Q variant in complex with the covalent adduct formed between prFMN cofactor and cinnamic acid (Int2)==
+<StructureSection load='6r3f' size='340' side='right'caption='[[6r3f]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
-Authors: Bailey, S.S., Leys, D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6r3f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R3F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6R3F FirstGlance]. <br>
-Description: Aspergillus niger ferulic acid decarboxylase (Fdc) E282Q variant in complex with the covalent adduct formed between prFMN cofactor and cinnamic acid (Int2)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JQK:[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-[(16~{R})-11,12,14,14-tetramethyl-5-oxidanyl-3-oxidanylidene-16-(2-phenylethyl)-1,4,6,8-tetrazatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-2(7),5,9(17),10,12-pentaen-8-yl]pentyl]+dihydrogen+phosphate'>JQK</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenacrylate_decarboxylase Phenacrylate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.102 4.1.1.102] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6r3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r3f OCA], [http://pdbe.org/6r3f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r3f RCSB], [http://www.ebi.ac.uk/pdbsum/6r3f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r3f ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/FDC1_ASPNC FDC1_ASPNC]] Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.[HAMAP-Rule:MF_03196]<ref>PMID:26083754</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Phenacrylate decarboxylase]]
+[[Category: Bailey, S S]]
 [[Category: Leys, D]]
-[[Category: Bailey, S.S]]
+[[Category: Lyase]]
+[[Category: Prfmn binding]]
+[[Category: Ubid]]