6mt7: Difference between revisions
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<StructureSection load='6mt7' size='340' side='right'caption='[[6mt7]], [[Resolution|resolution]] 1.78Å' scene=''> | <StructureSection load='6mt7' size='340' side='right'caption='[[6mt7]], [[Resolution|resolution]] 1.78Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6mt7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MT7 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6mt7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Phlebotomus_duboscqi Phlebotomus duboscqi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MT7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MT7 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=TRT:FRAGMENT+OF+TRITON+X-100'>TRT</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mt7 OCA], [https://pdbe.org/6mt7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mt7 RCSB], [https://www.ebi.ac.uk/pdbsum/6mt7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mt7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/D7L_PHLDU D7L_PHLDU] Modulates blood feeding of female sandflies on vertebrate species by binding and sequestering different mediators involved in the host response (By similarity). Binds leukotriene C4, leukotriene D4, leukotriene E4 and U-46619, a stable analog of thromboxane A2 (PubMed:30926880). Does not bind histamine or serotonin (PubMed:30926880). Inhibits platelet aggregation induced by low concentrations of collagen in thromboxane A2-dependent manner (PubMed:30926880).[UniProtKB:P18153]<ref>PMID:30926880</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Phlebotomus duboscqi]] | ||
[[Category: | [[Category: Andersen JF]] | ||
[[Category: | [[Category: Jablonka W]] | ||