5yep: Difference between revisions

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<StructureSection load='5yep' size='340' side='right'caption='[[5yep]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='5yep' size='340' side='right'caption='[[5yep]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5yep]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sheon Sheon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YEP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YEP FirstGlance]. <br>
<table><tr><td colspan='2'>[[5yep]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Shewanella_oneidensis_MR-1 Shewanella oneidensis MR-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YEP FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SO_3165 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=211586 SHEON]), SO_3166 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=211586 SHEON])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yep OCA], [http://pdbe.org/5yep PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yep RCSB], [http://www.ebi.ac.uk/pdbsum/5yep PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yep ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yep OCA], [https://pdbe.org/5yep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yep RCSB], [https://www.ebi.ac.uk/pdbsum/5yep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yep ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MNTA_SHEON MNTA_SHEON] Antitoxin component of a type VII toxin-antitoxin (TA) system. Upon overexpression in situ or in E.coli neutralizes the effect of cognate toxin HepT (PubMed:26112399, PubMed:29555683, PubMed:33045733). Neutralization is mostly due to tri-AMPylation of toxin by this enzyme. Successively tri-AMPylates HepT on 'Tyr-104' (PubMed:33045733). Binds its own promoter, probably repressing its expression. The TA system confers plasmid stability in E.coli (PubMed:26112399).<ref>PMID:26112399</ref> <ref>PMID:29555683</ref> <ref>PMID:33045733</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Sheon]]
[[Category: Shewanella oneidensis MR-1]]
[[Category: Dong, Y H]]
[[Category: Dong YH]]
[[Category: Gao, Z Q]]
[[Category: Gao ZQ]]
[[Category: Jia, X]]
[[Category: Jia X]]
[[Category: Zhang, H]]
[[Category: Zhang H]]
[[Category: Antitoxin-toxin complex]]
[[Category: Hepn-mnt]]
[[Category: Toxin-antitoxin]]
Retrieved from "https://proteopedia.org/5yep"