Uncoupling Protein 2

Uncoupling Protein 2 (UCP2) in Diabetes

spinqualitylabelsall models Uncoupling Protein 2 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D This is a default text for your page Kimberly Jimenez: Uncoupling Protein 2. Click above on edit this page to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia or to the article describing Jmol to the rescue. Figure 1: Uncoupling Protein 2 Disease Mitochondria are found in the every cell in the human body and it acts as the "power house" of the cell. The mitochondria is called the "power house" because it converts the food consumtion and oxygen to energy to power the body. A mitochondrial disorder is caused by the mutation of mitochondrial DNA (mtDNA). This disorder is genetic transmitted from a parent and can be seen from birth or at an older age. These disorders are chronic disorders. Some of this disorders can be seen in figure 1. Figure 1: Mitochondrial Disorders The disorder which affects the pancreas is caused by the A3243G mutation which causes diabetes. Bilateral hearing impairment is a symptom carried by the carrier of mitochondrial diabetes. Some other symptoms that can be seen is a change in pigmentation of the retina. This mutation can be seen around the age of 38 years old, this disease is age dependent in the fact that over time there is a deterioration of glucose homeostasis. The pattern of inhertitance of this disorder depends on the mitochondria of the mother and can be passed down to both male and female offspring. Function This is a sample scene created with SAT to color by Group, and another to make a transparent representation of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

Proteopedia Page Contributors and Editors (what is this?)

Kimberly Jimenez, Michal Harel, Jaime Prilusky