6huf: Difference between revisions

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<StructureSection load='6huf' size='340' side='right'caption='[[6huf]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
<StructureSection load='6huf' size='340' side='right'caption='[[6huf]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6huf]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HUF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HUF FirstGlance]. <br>
<table><tr><td colspan='2'>[[6huf]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HUF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.82&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAB27A, RAB27 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6huf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6huf OCA], [http://pdbe.org/6huf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6huf RCSB], [http://www.ebi.ac.uk/pdbsum/6huf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6huf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6huf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6huf OCA], [https://pdbe.org/6huf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6huf RCSB], [https://www.ebi.ac.uk/pdbsum/6huf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6huf ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/RB27A_HUMAN RB27A_HUMAN]] Griscelli syndrome type 2. The disease is caused by mutations affecting the gene represented in this entry.  
[https://www.uniprot.org/uniprot/RB27A_HUMAN RB27A_HUMAN] Griscelli syndrome type 2. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RB27A_HUMAN RB27A_HUMAN]] Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.<ref>PMID:18812475</ref>
[https://www.uniprot.org/uniprot/RB27A_HUMAN RB27A_HUMAN] Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.<ref>PMID:18812475</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6huf" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6huf" style="background-color:#fffaf0;"></div>
==See Also==
*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Cota, E]]
[[Category: Cota E]]
[[Category: Jamshidiha, M]]
[[Category: Jamshidiha M]]
[[Category: Murray, J W]]
[[Category: Murray JW]]
[[Category: Perez-Dorado, I]]
[[Category: Perez-Dorado I]]
[[Category: Read, R J]]
[[Category: Read RJ]]
[[Category: Tate, E W]]
[[Category: Tate EW]]
[[Category: Exocytosis]]
[[Category: Gtpase]]
[[Category: Vesicle transport]]
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