5n2a: Difference between revisions

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<StructureSection load='5n2a' size='340' side='right'caption='[[5n2a]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='5n2a' size='340' side='right'caption='[[5n2a]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5n2a]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanotorris_formicicus_mc-s-70 Methanotorris formicicus mc-s-70]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N2A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N2A FirstGlance]. <br>
<table><tr><td colspan='2'>[[5n2a]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanotorris_formicicus_Mc-S-70 Methanotorris formicicus Mc-S-70]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5N2A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=COM:1-THIOETHANESULFONIC+ACID'>COM</scene>, <scene name='pdbligand=F43:FACTOR+430'>F43</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=TP7:COENZYME+B'>TP7</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AGM:5-METHYL-ARGININE'>AGM</scene>, <scene name='pdbligand=GL3:THIOGLYCIN'>GL3</scene>, <scene name='pdbligand=MGN:2-METHYL-GLUTAMINE'>MGN</scene>, <scene name='pdbligand=MHS:N1-METHYLATED+HISTIDINE'>MHS</scene>, <scene name='pdbligand=TRX:6-HYDROXYTRYPTOPHAN'>TRX</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGM:5-METHYL-ARGININE'>AGM</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=COM:1-THIOETHANESULFONIC+ACID'>COM</scene>, <scene name='pdbligand=F43:FACTOR+430'>F43</scene>, <scene name='pdbligand=GL3:THIOGLYCIN'>GL3</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MGN:2-METHYL-GLUTAMINE'>MGN</scene>, <scene name='pdbligand=MHS:N1-METHYLATED+HISTIDINE'>MHS</scene>, <scene name='pdbligand=TP7:COENZYME+B'>TP7</scene>, <scene name='pdbligand=TRX:6-HYDROXYTRYPTOPHAN'>TRX</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coenzyme-B_sulfoethylthiotransferase Coenzyme-B sulfoethylthiotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.4.1 2.8.4.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5n2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n2a OCA], [https://pdbe.org/5n2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5n2a RCSB], [https://www.ebi.ac.uk/pdbsum/5n2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5n2a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n2a OCA], [http://pdbe.org/5n2a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n2a RCSB], [http://www.ebi.ac.uk/pdbsum/5n2a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n2a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/H1KXL5_9EURY H1KXL5_9EURY]] Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide.[PIRNR:PIRNR000262]  
[https://www.uniprot.org/uniprot/H1KXL5_9EURY H1KXL5_9EURY] Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide.[PIRNR:PIRNR000262]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Coenzyme-B sulfoethylthiotransferase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Methanotorris formicicus mc-s-70]]
[[Category: Methanotorris formicicus Mc-S-70]]
[[Category: Ermler, U]]
[[Category: Ermler U]]
[[Category: Shima, S]]
[[Category: Shima S]]
[[Category: Wagner, T]]
[[Category: Wagner T]]
[[Category: Wegner, C E]]
[[Category: Wegner CE]]
[[Category: Autotroph]]
[[Category: Binding site]]
[[Category: Catalysis]]
[[Category: Coenzyme]]
[[Category: Disulfide]]
[[Category: Hydrogen]]
[[Category: Hydrogen bonding]]
[[Category: Hydroxy-tryptophane]]
[[Category: Ligand]]
[[Category: Mesna]]
[[Category: Metalloporphyrin]]
[[Category: Methane]]
[[Category: Methanococcale]]
[[Category: Nickel]]
[[Category: Oxidation-reduction]]
[[Category: Oxidoreductase]]
[[Category: Phosphothreonine]]
[[Category: Post-translational modification]]
[[Category: Protein conformation]]
[[Category: Protein folding]]
[[Category: Protein structure]]
[[Category: Thermophile]]
[[Category: Transferase]]