Toxin Tx7335: Difference between revisions
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== Discovery == | == Discovery == | ||
Toxin Tx7335 was discovered during testing of eastern mamba venom. The experiment was attempting to identify the toxins that interact with the KcsA pathway but received false positives upon isolation of all known proteins that interact with this pathway. The experimenters proceeded to remove the known toxins from the venom and run the remaining venom over a free Co2+ resin before running toxin pull-down experiments. These experiments showed the presence of a single toxin with a mass of 7333.5 daltons (4). The mass of this protein was then used to name the toxin. [[Media: Toxin Tx7335 discovery.mp4]] | Toxin Tx7335 was discovered during testing of eastern mamba venom. The experiment was attempting to identify the toxins that interact with the KcsA pathway but received false positives upon isolation of all known proteins that interact with this pathway. The experimenters proceeded to remove the known toxins from the venom and run the remaining venom over a free Co2+ resin before running toxin pull-down experiments. These experiments showed the presence of a single toxin with a mass of 7333.5 daltons (4). The mass of this protein was then used to name the toxin. | ||
[[Media: Toxin Tx7335 discovery.mp4]] | |||
== Structural highlights == | == Structural highlights == | ||
