6ibs: Difference between revisions
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<StructureSection load='6ibs' size='340' side='right'caption='[[6ibs]], [[Resolution|resolution]] 1.37Å' scene=''> | <StructureSection load='6ibs' size='340' side='right'caption='[[6ibs]], [[Resolution|resolution]] 1.37Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6ibs]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6ibs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IBS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IBS FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HB8:[7-[(2-methylpropan-2-yl)oxycarbonylamino]-1-benzothiophen-2-yl]-tris(oxidanyl)boranuide'>HB8</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HB8:[7-[(2-methylpropan-2-yl)oxycarbonylamino]-1-benzothiophen-2-yl]-tris(oxidanyl)boranuide'>HB8</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ibs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ibs OCA], [https://pdbe.org/6ibs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ibs RCSB], [https://www.ebi.ac.uk/pdbsum/6ibs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ibs ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 6ibs" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6ibs" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Klebsiella pneumoniae]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bellio | [[Category: Bellio P]] | ||
[[Category: Celenza | [[Category: Celenza G]] | ||
[[Category: Cendron | [[Category: Cendron L]] | ||
[[Category: Costi | [[Category: Costi MP]] | ||
[[Category: Maso | [[Category: Maso L]] | ||
[[Category: Montanari | [[Category: Montanari M]] | ||
[[Category: Quotadamo | [[Category: Quotadamo A]] | ||
[[Category: Tondi | [[Category: Tondi D]] | ||
[[Category: Venturelli | [[Category: Venturelli A]] | ||
Latest revision as of 11:51, 24 January 2024
Crystal structure of NDM-1 beta-lactamase in complex with boronic inhibitor cpd 6
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