4r2y: Difference between revisions

<table><tr><td colspan='2'>[[4r2y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R2Y FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r2y OCA], [https://pdbe.org/4r2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r2y RCSB], [https://www.ebi.ac.uk/pdbsum/4r2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r2y ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/APC11_HUMAN APC11_HUMAN] Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.<ref>PMID:11739784</ref> <ref>PMID:18485873</ref>  

[[Category: Homo sapiens]]

[[Category: Alsharif O]]

[[Category: Bao J]]

[[Category: Brown NG]]

[[Category: Cho SE]]

[[Category: Dube P]]

[[Category: Frye JJ]]

[[Category: Grace CRR]]

[[Category: Jarvis MA]]

[[Category: Kurinov I]]

[[Category: Nourse A]]

[[Category: Peters JM]]

[[Category: Petzold G]]

[[Category: Qiao R]]

[[Category: Schulman BA]]

[[Category: Stark H]]

[[Category: Vanderlinden R]]

[[Category: Watson ER]]

[[Category: Weissmann F]]

[[Category: Zheng J]]