4r8e: Difference between revisions

Line 3:

== Structural highlights ==

<table><tr><td colspan='2'>[[4r8e]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus~~ pestis~~" (lehmann and neumann 1896) migula 1900~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8E OCA]. For a guided tour on the structure components use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4R8E FirstGlance].

<table><tr><td colspan='2'>[[4r8e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8E OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=4R8E FirstGlance].

</td></tr><tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">fabF, fabF4, y1760, YP_2253, YPO1601 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 "Bacillus pestis" (Lehmann and Neumann 1896) Migula 1900])</td></tr>

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=4r8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8e OCA], [https://pdbe.org/4r8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r8e RCSB], [https://www.ebi.ac.uk/pdbsum/4r8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8e ProSAT]</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_II Beta-ketoacyl-[acyl-carrier-protein] synthase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.179 2.3.1.179] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4r8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8e OCA], [~~http~~://pdbe.org/4r8e PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4r8e RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4r8e PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8e ProSAT]</td></tr>

</table>

== Function ==

[~~[http~~://www.uniprot.org/uniprot/~~Q7CJ22_YERPE Q7CJ22_YERPE]~~] Catalyzes the ~~condensation reaction~~ of ~~fatty acid synthesis~~ by the addition to an acyl acceptor of ~~two carbons from malonyl~~-ACP.[PIRNR:PIRNR000447]

[https://www.uniprot.org/uniprot/A0A3N4B474_YERPE A0A3N4B474_YERPE] Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.[PIRNR:PIRNR000447]

== Publication Abstract from PubMed ==

Line 27:

Line 25:

</StructureSection>

[[Category: Large Structures]]

[[Category: ~~Forwood, J K~~]]

[[Category: Yersinia pestis]]

[[Category: ~~Himiari, Z~~]]

[[Category: Forwood JK]]

[[Category: ~~Nanson, J D~~]]

[[Category: Himiari Z]]

[[Category: ~~Swarbrick, C M.D~~]]

[[Category: Nanson JD]]

[[Category: ~~Condensing enzyme]]~~

[[Category: Swarbrick CMD]]

~~[[Category: Fabf]]~~

~~[[Category: Kasii]]~~

~~[[Category: Thiolase fold]]~~

~~[[Category: Transferase~~]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 3: / Line 3: @@
 <StructureSection load='4r8e' size='340' side='right'caption='[[4r8e]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4r8e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R8E FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4r8e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R8E FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabF, fabF4, y1760, YP_2253, YPO1601 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 "Bacillus pestis" (Lehmann and Neumann 1896) Migula 1900])</td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8e OCA], [https://pdbe.org/4r8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r8e RCSB], [https://www.ebi.ac.uk/pdbsum/4r8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8e ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_II Beta-ketoacyl-[acyl-carrier-protein] synthase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.179 2.3.1.179] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8e OCA], [http://pdbe.org/4r8e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r8e RCSB], [http://www.ebi.ac.uk/pdbsum/4r8e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8e ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/Q7CJ22_YERPE Q7CJ22_YERPE]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.[PIRNR:PIRNR000447]
+[https://www.uniprot.org/uniprot/A0A3N4B474_YERPE A0A3N4B474_YERPE] Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.[PIRNR:PIRNR000447]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 27: / Line 25: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Forwood, J K]]
+[[Category: Yersinia pestis]]
-[[Category: Himiari, Z]]
+[[Category: Forwood JK]]
-[[Category: Nanson, J D]]
+[[Category: Himiari Z]]
-[[Category: Swarbrick, C M.D]]
+[[Category: Nanson JD]]
-[[Category: Condensing enzyme]]
+[[Category: Swarbrick CMD]]
-[[Category: Fabf]]
-[[Category: Kasii]]
-[[Category: Thiolase fold]]
-[[Category: Transferase]]