1a0l: Difference between revisions

<table><tr><td colspan='2'>[[1a0l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A0L FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=APA:(2S)-3-(4-CARBAMIMIDOYLPHENYL)-2-HYDROXYPROPANOIC+ACID'>APA</scene></td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptase Tryptase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.59 3.4.21.59] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0l OCA], [http://pdbe.org/1a0l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a0l RCSB], [http://www.ebi.ac.uk/pdbsum/1a0l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1a0l ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/TRYB2_HUMAN TRYB2_HUMAN]] Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Has an immunoprotective role during bacterial infection. Required to efficiently combat K.pneumoniae infection (By similarity).