4txp: Difference between revisions

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<StructureSection load='4txp' size='340' side='right'caption='[[4txp]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
<StructureSection load='4txp' size='340' side='right'caption='[[4txp]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4txp]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TXP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TXP FirstGlance]. <br>
<table><tr><td colspan='2'>[[4txp]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TXP FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4txq|4txq]], [[4txr|4txr]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4txp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4txp OCA], [https://pdbe.org/4txp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4txp RCSB], [https://www.ebi.ac.uk/pdbsum/4txp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4txp ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VTA1, C6orf55, HSPC228, My012 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4txp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4txp OCA], [http://pdbe.org/4txp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4txp RCSB], [http://www.ebi.ac.uk/pdbsum/4txp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4txp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VTA1_HUMAN VTA1_HUMAN]] Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding.<ref>PMID:15644320</ref>
[https://www.uniprot.org/uniprot/VTA1_HUMAN VTA1_HUMAN] Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding.<ref>PMID:15644320</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Vacuolar protein sorting-associated protein|Vacuolar protein sorting-associated protein]]
*[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Vild, C J]]
[[Category: Vild CJ]]
[[Category: Xu, Z]]
[[Category: Xu Z]]
[[Category: Escrt]]
[[Category: Mit]]
[[Category: Mit domain]]
[[Category: Protein transport]]
Retrieved from "https://proteopedia.org/4txp"