1a0m: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[1a0m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0M OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1A0M FirstGlance]. <br>

<table><tr><td colspan='2'>[[1a0m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A0M FirstGlance]. <br>

</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1a0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0m OCA], [~~http~~://pdbe.org/1a0m PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1a0m RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1a0m PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1a0m ProSAT]</span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0m OCA], [https://pdbe.org/1a0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a0m RCSB], [https://www.ebi.ac.uk/pdbsum/1a0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a0m ProSAT]</span></td></tr>

</table>

== Function ==

[[~~http~~://www.uniprot.org/uniprot/CA1_CONEP CA1_CONEP]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This peptide blocks mammalian nicotinic acetylcholine receptors composed of alpha-3/beta-2 and alpha-3/beta-4 subunits.

[[https://www.uniprot.org/uniprot/CA1_CONEP CA1_CONEP]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This peptide blocks mammalian nicotinic acetylcholine receptors composed of alpha-3/beta-2 and alpha-3/beta-4 subunits.

== Publication Abstract from PubMed ==

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 <StructureSection load='1a0m' size='340' side='right'caption='[[1a0m]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1a0m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A0M FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1a0m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A0M FirstGlance]. <br>
 </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0m OCA], [http://pdbe.org/1a0m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a0m RCSB], [http://www.ebi.ac.uk/pdbsum/1a0m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1a0m ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a0m OCA], [https://pdbe.org/1a0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a0m RCSB], [https://www.ebi.ac.uk/pdbsum/1a0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a0m ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/CA1_CONEP CA1_CONEP]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This peptide blocks mammalian nicotinic acetylcholine receptors composed of alpha-3/beta-2 and alpha-3/beta-4 subunits.
+[[https://www.uniprot.org/uniprot/CA1_CONEP CA1_CONEP]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This peptide blocks mammalian nicotinic acetylcholine receptors composed of alpha-3/beta-2 and alpha-3/beta-4 subunits.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==