6jxi: Difference between revisions
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==Rb+-bound E2-MgF state of the gastric proton pump (Tyr799Trp)== | |||
<StructureSection load='6jxi' size='340' side='right'caption='[[6jxi]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6jxi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JXI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JXI FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CE1:O-DODECANYL+OCTAETHYLENE+GLYCOL'>CE1</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=MF4:TETRAFLUOROMAGNESATE(2-)'>MF4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene>, <scene name='pdbligand=RB:RUBIDIUM+ION'>RB</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/H(+)/K(+)-exchanging_ATPase H(+)/K(+)-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=7.2.2.19 7.2.2.19] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jxi OCA], [http://pdbe.org/6jxi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jxi RCSB], [http://www.ebi.ac.uk/pdbsum/6jxi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jxi ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/ATP4B_PIG ATP4B_PIG]] Note=Parietal cell autoantigen associated with autoimmune gastritis. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ATP4A_PIG ATP4A_PIG]] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Abe, K]] | |||
[[Category: Irie, K]] | [[Category: Irie, K]] | ||
[[Category: | [[Category: Gastric]] | ||
[[Category: Ion pump]] | |||
[[Category: Membrane protein]] | |||
[[Category: P-type atpase]] | |||
[[Category: Proton pump]] | |||