4wpf: Difference between revisions

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<StructureSection load='4wpf' size='340' side='right'caption='[[4wpf]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4wpf' size='340' side='right'caption='[[4wpf]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4wpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WPF FirstGlance]. <br>
<table><tr><td colspan='2'>[[4wpf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WPF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3SN:N-[4-(4-ACETYLPIPERAZIN-1-YL)-2-FLUOROBENZYL]-N-CYCLOBUTYLBENZENESULFONAMIDE'>3SN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3SN:N-[4-(4-ACETYLPIPERAZIN-1-YL)-2-FLUOROBENZYL]-N-CYCLOBUTYLBENZENESULFONAMIDE'>3SN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RORC, NR1F3, RORG, RZRG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wpf OCA], [https://pdbe.org/4wpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wpf RCSB], [https://www.ebi.ac.uk/pdbsum/4wpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wpf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wpf OCA], [http://pdbe.org/4wpf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wpf RCSB], [http://www.ebi.ac.uk/pdbsum/4wpf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wpf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RORG_HUMAN RORG_HUMAN]] Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T-helper cells into Th17 cells. Regulate the expression of several components of the circadian clock.  
[https://www.uniprot.org/uniprot/RORG_HUMAN RORG_HUMAN] Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T-helper cells into Th17 cells. Regulate the expression of several components of the circadian clock.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Boenig, G de Leon]]
[[Category: Hymowitz SG]]
[[Category: Hymowitz, S G]]
[[Category: Kiefer JR]]
[[Category: Kiefer, J R]]
[[Category: Wallweber HA]]
[[Category: Wallweber, H A]]
[[Category: De Leon Boenig G]]
[[Category: Nuclear receptor]]
[[Category: Ror]]
[[Category: Rorc]]
[[Category: Rorg]]
[[Category: Transcription]]
Retrieved from "https://proteopedia.org/4wpf"