4uvi: Difference between revisions

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<StructureSection load='4uvi' size='340' side='right'caption='[[4uvi]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
<StructureSection load='4uvi' size='340' side='right'caption='[[4uvi]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4uvi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UVI FirstGlance]. <br>
<table><tr><td colspan='2'>[[4uvi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UVI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KXU:5-{[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYL]METHYL}-N-[(2-METHYLPYRIDIN-4-YL)METHYL]-1,2-OXAZOLE-3-CARBOXAMIDE'>KXU</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KXU:5-{[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYL]METHYL}-N-[(2-METHYLPYRIDIN-4-YL)METHYL]-1,2-OXAZOLE-3-CARBOXAMIDE'>KXU</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uvd|4uvd]], [[4uve|4uve]], [[4uvg|4uvg]], [[4uvh|4uvh]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uvi OCA], [https://pdbe.org/4uvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uvi RCSB], [https://www.ebi.ac.uk/pdbsum/4uvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uvi ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uvi OCA], [http://pdbe.org/4uvi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uvi RCSB], [http://www.ebi.ac.uk/pdbsum/4uvi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uvi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU]


==See Also==
==See Also==
*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]
*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Cowan, S]]
[[Category: Cowan S]]
[[Category: Ghorpade, S]]
[[Category: Ghorpade S]]
[[Category: Gingell, H]]
[[Category: Gingell H]]
[[Category: Madhavapeddi, P]]
[[Category: Madhavapeddi P]]
[[Category: Read, J A]]
[[Category: Read JA]]
[[Category: Acp enoyl reductase]]
[[Category: Fblg]]
[[Category: Inha]]
[[Category: Oxidoreductase]]
[[Category: Pyrimidine isoxazole]]

Revision as of 07:42, 29 March 2023

Discovery of pyrimidine isoxazoles InhA in complex with compound 23

4uvi, resolution 1.73Å

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