5qsp: Difference between revisions

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'''Unreleased structure'''


The entry 5qsp is ON HOLD
==PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434929==
 
<StructureSection load='5qsp' size='340' side='right'caption='[[5qsp]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
Authors: Newman, J.A., Katis, V.L., Gavard, A.E., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5qsp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QSP FirstGlance]. <br>
Description: PanDDA analysis group deposition --Crystal Structure of human STAG1 in complex with Z2856434929
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LVV:4-[(4-methylphenyl)methyl]-1,4-thiazinane+1,1-dioxide'>LVV</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qsp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qsp OCA], [http://pdbe.org/5qsp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qsp RCSB], [http://www.ebi.ac.uk/pdbsum/5qsp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qsp ProSAT]</span></td></tr>
[[Category: Katis, V.L]]
</table>
[[Category: Arrowsmith, C.H]]
== Disease ==
[[http://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN]] STAG1-related intellectual disability-facial dysmorphism-gastroesophageal reflux syndrome. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[[http://www.uniprot.org/uniprot/STAG1_HUMAN STAG1_HUMAN]] Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Delft, F von]]
[[Category: Edwards, A]]
[[Category: Gavard, A E]]
[[Category: Gileadi, O]]
[[Category: Gileadi, O]]
[[Category: Newman, J.A]]
[[Category: Katis, V L]]
[[Category: Edwards, A]]
[[Category: Newman, J A]]
[[Category: Gavard, A.E]]
[[Category: Pandda]]
[[Category: Von Delft, F]]
[[Category: Sgc - diamond i04-1 fragment screening]]
[[Category: Bountra, C]]
[[Category: Transcription]]
[[Category: Xchemexplorer]]

Revision as of 05:47, 21 August 2019

PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434929

5qsp, resolution 2.89Å

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