5zjf: Difference between revisions
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==LDHA-MA== | |||
<StructureSection load='5zjf' size='340' side='right'caption='[[5zjf]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5zjf]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZJF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZJF FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9G9:5,5-[(2R,3S)-2,3-dimethylbutane-1,4-diyl]bis(2H-1,3-benzodioxole)'>9G9</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zjf OCA], [http://pdbe.org/5zjf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zjf RCSB], [http://www.ebi.ac.uk/pdbsum/5zjf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zjf ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/LDHA_HUMAN LDHA_HUMAN]] Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:[http://omim.org/entry/612933 612933]]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.<ref>PMID:2334430</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: L-lactate dehydrogenase]] | |||
[[Category: Large Structures]] | |||
[[Category: Han, C W]] | |||
[[Category: Jang, S B]] | |||
[[Category: Inhibitor]] | |||
[[Category: Ldha]] | |||
[[Category: Machilin some]] | |||
[[Category: Oxidoreductase]] | |||
