4y1t: Difference between revisions

<table><tr><td colspan='2'>[[4y1t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y1T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y1T FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y1t OCA], [https://pdbe.org/4y1t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y1t RCSB], [https://www.ebi.ac.uk/pdbsum/4y1t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y1t ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/PERF_MOUSE PERF_MOUSE] Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.<ref>PMID:3261391</ref> <ref>PMID:8164737</ref> <ref>PMID:7526382</ref> <ref>PMID:19446473</ref> <ref>PMID:21037563</ref>  

[[Category: Mus musculus]]

[[Category: Conroy PJ]]

[[Category: Norton RS]]

[[Category: Whisstock JC]]

[[Category: Yagi H]]