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| </StructureSection> | | </StructureSection> |
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| == 3D Structures of DNA ligase ==
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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| {{#tree:id=OrganizedByTopic|openlevels=0|
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| *ATP-dependent LigD
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| **[[3p4h]], [[3ta5]], [[3ta7]] – LigD N-terminal – ''Candidatus korarchaeum cryptofilum''<br />
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| **[[3gde]] – LigD – ''Archaeoglobus fulgidus''<br />
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| **[[2hiv]] – SsLigD – ''Sulfolobus solfataricus''<br />
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| **[[2hix]] - SsLigD + ATP<br />
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| **[[2cfm]] - LigD + AMP – ''Pyrococcus furiosus''<br />
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| **[[2fao]] - PaLigD polymerase domain – ''Pseudomonas aeruginosa''<br />
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| **[[2faq]], [[2far]] - PaLigD polymerase domain + ATP + Mn<br />
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| **[[1a0i]] – LigD (mutant) + ATP – Bacteriophage T7<br />
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| **[[4eq5]] – LigD + AMP – ''Thermococcus sibiricus''<br />
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| **[[4d05]] – LigD + AMP - ''Psychromonas'' <br />
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| **[[6nhx]], [[6nhz]] – MtLigD D + ATP - ''Mycobacterium tuberculosis'' <br />
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| *NAD+-dependent LigD
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| **[[3jsl]], [[3jsn]] - SaLigD adenylation domain – ''Staphylococcus aureus''<br />
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| **[[4cc5]], [[4cc6]], [[5fpo]], [[5fpr]] – SaLigD adenylation domain + inhibitor <br />
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| **[[3ba8]], [[3ba9]], [[3baa]], [[3bab]], [[3bac]], [[4eeq]], [[4efb]], [[4efe]], [[4lh6]], [[4lh7]] - EfLigD adenylation domain + NMN + inhibitor – ''Enterococcus faecalis''<br />
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| **[[1ta8]], [[1tae]] - EfLigD adenylation domain<br />
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| **[[1zau]] - MtLigD adenylation domain <br />
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| **[[3sgi]] – MtLigD (mutant) + AMP<br />
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| **[[1v9p]], [[1dgs]] – LigD – ''Thermos filiformis''<br />
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| **[[1b04]] – LigD adenylation domain (mutant) – ''Geobacillus stearothermophilus''<br />
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| **[[4glw]] – LigD A + NMN + inhibitor – ''Streptococcus pneumoniae''<br />
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| **[[4glx]] – EcLigD + DNA + inhibitor - ''Escherichia coli''<br />
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| **[[5tt5]] - EciLigD + NAD<br />
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| **[[3pn1]], [[4uco]], [[4ucr]], [[4ucs]], [[4uct]], [[4ucu]], [[4ucv]], [[4ufz]] – HiLigD adenylation domain + inhibitor – Haemophilus influenza<br />
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| **[[3uq8]] - HiLigD adenylation domain + NAD<br />
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| *LigD
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| **[[2q2t]] – CvLigD + DNA + AMP + CMP – Chlorella virus<br />
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| **[[6imj]], [[6imk]], [[6iml]], [[6imn]] – LigD + DNA – African swine fever virus<br />
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| **[[6gdr]] – LigD + DNA – ''Alteromonas mediterranea''<br />
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| **[[6dt1]] – T4LigD + DNA – phage T4<br />
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| **[[5wfy]] – T4LigD DNA-binding domain <br />
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| **[[2q2u]], [[ 1p8l]], [[ 1fvi]] - CvLigD + DNA + mononucleotide<br />
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| **[[2owo]] – LigD + DNA + AMP + CMP – ''Escherichia coli''<br />
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| **[[3qwu]] – LigD – ''Aquifex aeolicus''<br />
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| **[[1l7b]] – LigD BRCT domain – ''Thermos thermophilus'' - NMR<br />
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| **[[3rr5]] – LigD - ''Thermococcus''<br />
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| **[[5frq]] - LigD + DNA polymerase III subunit β – ''Helicobacter pylori''<br />
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| *Mammalian LigD I
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| **[[1x9n]] – hLigD I + DNA + AMP + CMP – human<br />
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| **[[2od8]] – LigD I residues 32-53 + PCNA
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| *Mammalian LigD III
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| **[[3l2p]] – hLigD III residues 257-833 + DNA<br />
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| **[[1uw0]] - hLigD III zinc-finger domain residues 1-117 – NMR<br />
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| **[[1imo]], [[1in1]] - hLigD III BRCTdomain – NMR<br />
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| **[[3pc7]] - hLigD III BRCTdomain<br />
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| **[[3pc8]] - hLigD III BRCTdomain (mutant) + XRCC1<br />
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| **[[3qvg]] - hLigD III BRCTdomain + XRCC1
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| *Mammalian LigD IV
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| **[[3ii6]], [[ 1ik9]] – hLigD IV C-terminal BRCT domains + DNA repair protein XRCC4<br />
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| **[[3w5o]] - hLigD IV <br />
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| **[[2e2w]] - hLigD IV BRCT domain - NMR<br />
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| **[[3vnn]] - hLigD IV adenylation domain<br />
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| **[[4hto]] - hLigD IV DNA-binding domain<br />
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| **[[4htp]] - hLigD IV DNA-binding domain + artemis protein peptide<br />
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| **[[3w1b]], [[3w1g]] - hLigD IV adenylation and DNA-binding domains + artemis protein peptide<br />
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| **[[6bkg]], [[6bkf]] - hLigD IV + DNA<br />
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| **[[1z56]] – LigD IV + ligase interacting factor 1 - yeast<br />
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| }}
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| == References == | | == References == |
