6i57: Difference between revisions
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==NMR structure of the third TPR domain of the human SPAG1 protein== | ==NMR structure of the third TPR domain of the human SPAG1 protein== | ||
<StructureSection load='6i57' size='340' side='right'caption='[[6i57 | <StructureSection load='6i57' size='340' side='right'caption='[[6i57]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6i57]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6i57]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6I57 FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6i57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i57 OCA], [https://pdbe.org/6i57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6i57 RCSB], [https://www.ebi.ac.uk/pdbsum/6i57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6i57 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/SPAG1_HUMAN SPAG1_HUMAN] Primary ciliary dyskinesia. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/SPAG1_HUMAN SPAG1_HUMAN] May play a role in the cytoplasmic assembly of the ciliary dynein arms (By similarity). May play a role in fertilization. Binds GTP and has GTPase activity.<ref>PMID:11517287</ref> <ref>PMID:1299558</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chagot | [[Category: Chagot ME]] | ||
[[Category: Quinternet | [[Category: Quinternet M]] | ||
