4zsk: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 3: Line 3:
<StructureSection load='4zsk' size='340' side='right'caption='[[4zsk]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='4zsk' size='340' side='right'caption='[[4zsk]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4zsk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strco Strco]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZSK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZSK FirstGlance]. <br>
<table><tr><td colspan='2'>[[4zsk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZSK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZSK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=16G:N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE'>16G</scene>, <scene name='pdbligand=4QY:BETA-N-ACETYLGLUCOSAMINE-6-PHOSPHATE'>4QY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=16G:N-ACETYL-D-GLUCOSAMINE-6-PHOSPHATE'>16G</scene>, <scene name='pdbligand=4QY:BETA-N-ACETYLGLUCOSAMINE-6-PHOSPHATE'>4QY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dasR, SCO5231, SC7E4.28c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=100226 STRCO])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zsk OCA], [https://pdbe.org/4zsk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zsk RCSB], [https://www.ebi.ac.uk/pdbsum/4zsk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zsk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zsk OCA], [http://pdbe.org/4zsk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zsk RCSB], [http://www.ebi.ac.uk/pdbsum/4zsk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zsk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DASR_STRCO DASR_STRCO]] Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N-acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin, as well as several genes involved in development, thereby linking carbon availability to morphogenesis. Binds to the DNA consensus sequence 5'-ACTGGTCTAGACCACT-3'.<ref>PMID:15247334</ref> <ref>PMID:16925557</ref>
[https://www.uniprot.org/uniprot/DASR_STRCO DASR_STRCO] Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N-acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin, as well as several genes involved in development, thereby linking carbon availability to morphogenesis. Binds to the DNA consensus sequence 5'-ACTGGTCTAGACCACT-3'.<ref>PMID:15247334</ref> <ref>PMID:16925557</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 24: Line 23:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Strco]]
[[Category: Fillenberg SB]]
[[Category: Fillenberg, S B]]
[[Category: Muller YA]]
[[Category: Muller, Y A]]
[[Category: Bacterial transcription regulation]]
[[Category: Effector-binding domain]]
[[Category: Gntr/hutc family]]
[[Category: Master regulator]]
[[Category: N-acetylglucosamine utilization]]
[[Category: N-acetylglucosamine-6-phosphate]]
[[Category: Repressor]]
[[Category: Transcription]]
[[Category: Transcription factor]]