|
|
| Line 1: |
Line 1: |
| <StructureSection load="2f6s" size="350" color="" frame="true" spin="on" Scene= side="right" caption='Filamentation protein complex with phosphate and Zn+2 (grey), [[2f6s]]' > | | <StructureSection load="2f6s" size="350" color="" frame="true" spin="on" Scene= side="right" caption='Filamentation protein complex with phosphate and Zn+2 (grey), [[2f6s]]' > |
| | |
| | __TOC__ |
| | |
| == Function == | | == Function == |
|
| |
|
| Line 55: |
Line 58: |
|
| |
|
| </StructureSection> | | </StructureSection> |
| == 3D structure of Fic protein ==
| |
| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| |
| {{#tree:id=OrganizedByTopic|openlevels=0|
| |
|
| |
| *Fic protein
| |
|
| |
| **[[4u04]], [[4u07]] – hFic – human <br />
| |
| **[[3cuc]] – Fic – ''Bacterioides thetaiotaomicron''<br />
| |
| **[[3eqx]] – SoFic – ''Shewanella oneidensis''<br />
| |
| **[[4rgl]] – Fic – ''Desulfovibrio alaskensis'' <br />
| |
| **[[4x2e]] – PdFic – ''Peptoclostridium difficile'' <br />
| |
| **[[4x2c]] – PdFic (mutant) <br />
| |
| **[[2f6s]] – Fic – ''Helicobacter pylori'' <br />
| |
| **[[6er8]], [[6erb]] – EfFic – ''Enterococcus faecalis'' <br />
| |
|
| |
| *Fic protein complex
| |
|
| |
|
| **[[4u0u]] – hFic + ADP <br />
| |
| **[[4u0s]] – hFic (mutant) + ADP <br />
| |
| **[[4u0z]] – hFic + APCPP <br />
| |
| **[[3s6a]] – NmFic + AMPPNP – ''Nisseria meningitidis''<br />
| |
| **[[3se5]], [[3sn9]], [[3zlm]] – NmFic (mutant) + AMPPNP <br />
| |
| **[[3zcn]] – SoFic Fic domain (mutant) + ATP <br />
| |
| **[[3zec]] – SoFic Fic domain (mutant) + AMPPNP <br />
| |
| **[[4x2d]] – PdFic (mutant) + ATP <br />
| |
| **[[6ep0]] – EfFic + AMP <br />
| |
| **[[6ep2]], [[6ep5]] – EfFic + ADP <br />
| |
| }}
| |
| == References == | | == References == |
| <references/> | | <references/> |
|
Function
Fic protein (Filamentation Induced by cAMP) is involved in cell division[1].
Structural highlights
2f6s is a 2 chains structure of sequences from Helicobacter pylori. Full crystallographic information is available from OCA.
Chain A
Active site (residues 96-103: HPFLEGNG)
Active site labelled
Active site + Zn
Active site + PO4
Active site + Zn + PO4
2g03 is a 1 chain structure of sequence from Neisseria meningitidis. Full crystallographic information is available from OCA.
Chain A
Active site (residues 107-114: HPFLEGNG)
Active site labelled
Active site + spacefill
3cuc is a 2 chains structure of sequences from Bacteria. Full crystallographic information is available from OCA.
Chain A
Active site (residues 192-199: HPFEDGNG)
Active site labelled
Active site + spacefill
3eqx is a Single protein structure of sequence from Shewanella oneidensis. Full crystallographic information is available from OCA.
Chain A
Active site (residues 198-205: HPFIDGNG)
Active site labelled
Active site + spacefill
3D structure of Fic protein
Fic protein 3D structures
|
References
Created with the participation of Tilman Schirmer.
