6pjj: Difference between revisions

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'''Unreleased structure'''


The entry 6pjj is ON HOLD
==Human PRPF4B bound to benzothiophene inhibitor 224==
 
<StructureSection load='6pjj' size='340' side='right'caption='[[6pjj]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
Authors: Godoi, P.H.C., Santiago, A.S., Fala, A.M., Ramos, P.Z., Sriranganadane, D., Mascarello, A., Segretti, N., Azevedo, H., Guimaraes, C.R.W., Arruda, P., Elkins, J.M., Counago, R.M., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6pjj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PJJ FirstGlance]. <br>
Description: Human PRPF4B bound to benzothiophene inhibitor 224
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OCJ:4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide'>OCJ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
[[Category: Fala, A.M]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
[[Category: Elkins, J.M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pjj OCA], [http://pdbe.org/6pjj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pjj RCSB], [http://www.ebi.ac.uk/pdbsum/6pjj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pjj ProSAT]</span></td></tr>
[[Category: Guimaraes, C.R.W]]
</table>
[[Category: Segretti, N]]
== Function ==
[[http://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN]] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Arruda, P]]
[[Category: Arruda, P]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Santiago, A.S]]
[[Category: Sriranganadane, D]]
[[Category: Azevedo, H]]
[[Category: Azevedo, H]]
[[Category: Counago, R M]]
[[Category: Elkins, J M]]
[[Category: Fala, A M]]
[[Category: Godoi, P H.C]]
[[Category: Guimaraes, C R.W]]
[[Category: Mascarello, A]]
[[Category: Mascarello, A]]
[[Category: Counago, R.M]]
[[Category: Ramos, P Z]]
[[Category: Ramos, P.Z]]
[[Category: Structural genomic]]
[[Category: Godoi, P.H.C]]
[[Category: Santiago, A S]]
[[Category: Segretti, N]]
[[Category: Sriranganadane, D]]
[[Category: Serine/threonine-protein kinase prp4 homolog]]
[[Category: Sgc]]
[[Category: Splicing kinase prpf4b]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]
Retrieved from "https://proteopedia.org/6pjj"