6pno: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 6pno is ON HOLD~~

==Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(N-isopropylsulfamoyl)phenyl)acetamide==

~~Authors: Oakley, A.J.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[6pno]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PNO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PNO FirstGlance]. <br>

~~Description:~~ Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(N-isopropylsulfamoyl)phenyl)acetamide

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ORM:2-chloro-N-{4-chloro-3-[(propan-2-yl)sulfamoyl]phenyl}acetamide'>ORM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pno FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pno OCA], [http://pdbe.org/6pno PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pno RCSB], [http://www.ebi.ac.uk/pdbsum/6pno PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pno ProSAT]</span></td></tr>

[[Category: Oakley, A.J]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/GSTO1_HUMAN GSTO1_HUMAN]] Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.<ref>PMID:10783391</ref> <ref>PMID:11511179</ref> <ref>PMID:17226937</ref> <ref>PMID:18028863</ref> <ref>PMID:21106529</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Oakley, A J]]

[[Category: Glutathione transferase]]

[[Category: Inhibitor]]

[[Category: Transferase-transferase inhibitor complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6pno is ON HOLD
+==Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(N-isopropylsulfamoyl)phenyl)acetamide==
+<StructureSection load='6pno' size='340' side='right'caption='[[6pno]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
-Authors: Oakley, A.J.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6pno]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PNO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PNO FirstGlance]. <br>
-Description: Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(N-isopropylsulfamoyl)phenyl)acetamide
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ORM:2-chloro-N-{4-chloro-3-[(propan-2-yl)sulfamoyl]phenyl}acetamide'>ORM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pno FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pno OCA], [http://pdbe.org/6pno PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pno RCSB], [http://www.ebi.ac.uk/pdbsum/6pno PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pno ProSAT]</span></td></tr>
-[[Category: Oakley, A.J]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/GSTO1_HUMAN GSTO1_HUMAN]] Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.<ref>PMID:10783391</ref> <ref>PMID:11511179</ref> <ref>PMID:17226937</ref> <ref>PMID:18028863</ref> <ref>PMID:21106529</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Oakley, A J]]
+[[Category: Glutathione transferase]]
+[[Category: Inhibitor]]
+[[Category: Transferase-transferase inhibitor complex]]