Glycated hemoglobin: Difference between revisions

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'''Glycated Hemoglobin''' is a form of [[hemoglobin]] with sugars attached to certain amino acid side chains. When blood sugar levels in an individual are high for long periods of time (hyperglycemia) as is the case for [[diabetes}people with diabetes]]) when blood sugar is not managed, these sugar modifications accumulate. The so-called HbA1c test is used as a measure of hyperglycemia over the past 3 months. The time span of 3 months corresponds to the average time red blood cells remain in the blood stream. When they are replenished by fresh cells, these carry hemoglobin that does not yet have the modification <ref>https://pdb101.rcsb.org/global-health/diabetes-mellitus/monitoring/diagnosis?more=y</ref>.

'''Glycated Hemoglobin''' is a form of [[hemoglobin]] with sugars attached to certain amino acid side chains. When blood sugar levels in an individual are high for long periods of time (hyperglycemia) as is the case for [[diabetes|people with diabetes]]) when blood sugar is not managed, these sugar modifications accumulate. The so-called HbA1c test<ref>PMID: 25633966</ref> is used as a measure of hyperglycemia over the past ~3 months. The time span of 3 months corresponds roughly to the average time red blood cells remain in the blood stream. When they are replenished by fresh cells, these carry hemoglobin that does not yet have the modification <ref>https://pdb101.rcsb.org/global-health/diabetes-mellitus/monitoring/diagnosis?more=y</ref>.

==Structure==

Glycated hemoglobin: Difference between revisions

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Revision as of 13:39, 15 July 2019 view source Karsten Theis (talk \| contribs) Editor, Macro, Print3D 4,602 edits →Structure ← Older edit		Revision as of 13:41, 15 July 2019 view source Karsten Theis (talk \| contribs) Editor, Macro, Print3D 4,602 edits No edit summary Newer edit →
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	'''Glycated Hemoglobin''' is a form of [[hemoglobin]] with sugars attached to certain amino acid side chains. When blood sugar levels in an individual are high for long periods of time (hyperglycemia) as is the case for [[diabetes}people with diabetes]]) when blood sugar is not managed, these sugar modifications accumulate. The so-called HbA1c test is used as a measure of hyperglycemia over the past 3 months. The time span of 3 months corresponds to the average time red blood cells remain in the blood stream. When they are replenished by fresh cells, these carry hemoglobin that does not yet have the modification <ref>https://pdb101.rcsb.org/global-health/diabetes-mellitus/monitoring/diagnosis?more=y</ref>.		'''Glycated Hemoglobin''' is a form of [[hemoglobin]] with sugars attached to certain amino acid side chains. When blood sugar levels in an individual are high for long periods of time (hyperglycemia) as is the case for [[diabetes\|people with diabetes]]) when blood sugar is not managed, these sugar modifications accumulate. The so-called HbA1c test<ref>PMID: 25633966</ref> is used as a measure of hyperglycemia over the past ~3 months. The time span of 3 months corresponds roughly to the average time red blood cells remain in the blood stream. When they are replenished by fresh cells, these carry hemoglobin that does not yet have the modification <ref>https://pdb101.rcsb.org/global-health/diabetes-mellitus/monitoring/diagnosis?more=y</ref>.

	==Structure==		==Structure==