5lnm: Difference between revisions

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<StructureSection load='5lnm' size='340' side='right'caption='[[5lnm]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='5lnm' size='340' side='right'caption='[[5lnm]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5lnm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LNM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LNM FirstGlance]. <br>
<table><tr><td colspan='2'>[[5lnm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LNM FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CKI1, At2g47430, T30B22.27 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lnm OCA], [https://pdbe.org/5lnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lnm RCSB], [https://www.ebi.ac.uk/pdbsum/5lnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lnm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lnm OCA], [http://pdbe.org/5lnm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lnm RCSB], [http://www.ebi.ac.uk/pdbsum/5lnm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lnm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CKI1_ARATH CKI1_ARATH]] Essential protein. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. Required for the development of megagametophyte in female gametophyte (embryo sac) independently of cytokinin. Contributes to vascular bundle formation and secondary growth in a cytokinin-independent manner, probably by promoting the maintenance of mitotic activity and/or identity of procambial cells. Seems to influence and promote the cytokinin signaling pathway.<ref>PMID:10610126</ref> <ref>PMID:12426401</ref> <ref>PMID:12774227</ref> <ref>PMID:18077346</ref> <ref>PMID:19622803</ref> <ref>PMID:20363773</ref> <ref>PMID:8875940</ref>
[https://www.uniprot.org/uniprot/CKI1_ARATH CKI1_ARATH] Essential protein. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. Required for the development of megagametophyte in female gametophyte (embryo sac) independently of cytokinin. Contributes to vascular bundle formation and secondary growth in a cytokinin-independent manner, probably by promoting the maintenance of mitotic activity and/or identity of procambial cells. Seems to influence and promote the cytokinin signaling pathway.<ref>PMID:10610126</ref> <ref>PMID:12426401</ref> <ref>PMID:12774227</ref> <ref>PMID:18077346</ref> <ref>PMID:19622803</ref> <ref>PMID:20363773</ref> <ref>PMID:8875940</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arabidopsis thaliana]]
[[Category: Histidine kinase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Demo, G]]
[[Category: Demo G]]
[[Category: Hejatko, J]]
[[Category: Hejatko J]]
[[Category: Janda, L]]
[[Category: Janda L]]
[[Category: Jansen, S]]
[[Category: Jansen S]]
[[Category: Jasenakova, Z]]
[[Category: Jasenakova Z]]
[[Category: Kaderavek, P]]
[[Category: Kaderavek P]]
[[Category: Otrusinova, O]]
[[Category: Otrusinova O]]
[[Category: Pekarova, B]]
[[Category: Pekarova B]]
[[Category: Wimmerova, M]]
[[Category: Wimmerova M]]
[[Category: Zidek, L]]
[[Category: Zidek L]]
[[Category: Histidine kinase cki1]]
[[Category: Mutant]]
[[Category: Receiver domain]]
[[Category: Transferase]]