GTP-binding protein: Difference between revisions

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</StructureSection>
</StructureSection>
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__NOTOC__
== 3D Structures of GTP-binding protein ==


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*'''Small GTP-binding protein'''
**[[2eki]] – hGBP TGS domain – NMR - human<br />
**[[3r7w]], [[4arz]] – yGtr1 + Gtr2 – yeast<br />
**[[3kxk]], [[3kxl]] – SsHflx (mutant) - ''Sulfolobus solfataricus''<br />
**[[2qtf]] – SsHflx<br />
**[[2dyk]] – TtEngA N terminal – ''Thermus thermophilus'' - Cryo EM<br />
**[[5a9v]], [[4zci]] – EcBipA – ''Escherichia coli'' <br />
**[[4zck]] – EcBipA  C-terminal<br />
**[[1sul]] – BsYsxC - ''Bacillus subtilis''<br />
**[[2dwq]] – TtYchF<br />
**[[1udx]] – TtObg<br />
**[[1wxq]] – GBP – ''Pyrococcus horikoshii''<br />
**[[1yr6]] - PaGBP – ''Pyrococcus abyssi''<br />
**[[1ni3]] – YchF – ''Schizosaccharomyces pombe''<br />
**[[5oxf]], [[5owv]] – GBP – ''Campylobacter jejuni''<br />
*GTP-binding protein complex with nucleotide
**[[2nzj]] – hRem1 + GDP<br />
**[[3cbq]] – hRem2 + GDP<br />
**[[3q85]] – hRem2 G domain + GTP analog<br />
**[[4aii]] - rRem2 G domain + GDP - rat<br />
**[[2ohf]] – hOla1 + AMP-PCP<br />
**[[1e0a]] – hGBP (mutant) + GIP<br />
**[[2b8w]], [[2d4h]] – hGBP N terminal + GMP<br />
**[[2b92]] - hGBP N terminal + GDP<br />
**[[2bc9]] - hGBP N terminal + GPPNHP<br />
**[[1yr7]], [[1yr8]] – PaGBP + GTP<br />
**[[1yr9]], [[1yra]], [[1yrb]], [[2oxr]] – PaGBP + GDP<br />
**[[3kxi]], [[2qth]] – SsHflx + GDP<br />
**[[1yzn]] – yPt1 + GPPNHP<br />
**[[1ky2]] – yPt7 + GPPNHP<br />
**[[1ky3]] – yPt7 + GDP<br />
**[[4phg]] – yPt7 (mutant) + GTP<br />
**[[4phh]] – yPt7 (mutant) + GNP<br />
**[[4phf]] – yPt7 (mutant) + GDP<br />
**[[3rwm]], [[3rwo]] – yPt32 + GPPNHP<br />
**[[1ek0]] – yPt51 + GPPNHP<br />
**[[2hjg]], [[4dcs]], [[4dct]], [[4dcu]], [[4dcv]], [[4kyu]], [[5mbs]] – BsEngA + GDP<br />
**[[5m7h]] – BsEngA + GMPPNP<br />
**[[5x4b]] – BsEngA N-terminal + GDP<br />
**[[1svi]] – BsYsxC + GDP<br />
**[[1svw]] – BsYsxC + GMPPNP<br />
**[[1lnz]] – BsObg + GTP<br />
**[[5m04]] – BsObg + GDP<br />
**[[2dby]] – TtYchF + GDP<br />
**[[1wf3]] – Tt1341 + GNP<br />
**[[2gao]] - hSar1A + GDP<br />
**[[2fa9]] – ChSar1B (mutant) + GDP – Chinese hamster<br />
**[[2fmx]] - ChSar1B + GDP<br />
**[[5a9y]], [[4zcm]] – EcBipA + G-4-phosphate <br />
**[[5a9x]], [[5a9w]], [[4zcl]] – EcBipA + GDP <br />
**[[5dn8]] – EngA + GDP – ''Coxiella burnetti''<br />
*GTP-binding protein complex with protein
**[[3cue]] – yPt1 + transport protein subunits<br />
**[[2bcg]], [[1ukv]] - yPt1 + secretory pathway GDP-dissociation inhibitor<br />
**[[3cpj]] – yPt31 + Rab GDP-dissociation inhibitor<br />
**[[1m2o]] – ySar1 + protein transport protein sec23<br />
**[[6gni]] - ySar1 + protein transport protein sec23 + Sec24 + GNP<br />
**[[3syn]] – BsFlhf + ATP-binding protein<br />
*GTP-binding protein 3 (Atlastin-1)
**[[4idn]] – hGDP3 cytoplasmic domain + GNP<br />
**[[4ido]], [[4idq]], [[3q5d]], [[3q5e]], [[3qnu]], [[3qof]] – hGDP3 cytoplasmic domain + GDP<br />
**[[6b9f]], [[6b9e]], [[6b9d]] – hGDP3 cytoplasmic domain (mutant) + GDP<br />
* GTP-binding protein LepA
**[[3cb4]] – EcLepA <br />
**[[2ywe]] – AaLepA – ''Aquifex aeolicus''<br />
**[[4k8w]] – LepA – ''Streptococcus pyogenes''<br />
**[[2ywf]] – AaLepA + GMP-PNP<br />
**[[2ywg]] - AaLepA + GTP<br />
**[[2ywh]] - AaLepA + GDP<br />
**[[3deg]] – EcLepA + A-tRNA + P-tRNA + RPS12 + RPL11 – Cryo EM<br />
*G protein bound to a G protein-coupled receptor
**[[3sn6]] - human β-2 adrenergic receptor + cameloid antibody fragment bound by guanine nucleotide-binding protein G. '''This is the first structure of an activated [[G protein-coupled receptor]] in a complex with its G protein.'''
*'''Ras-related small GTP-binding protein'''
**[[3llu]] – hRag-C nucleotide-binding domain<br />
**[[2rhd]] – Rab-1a – ''Cryptosporidium parvum''<br />
*Ras-related small GTP-binding protein complex with nucleotide
**[[2l0x]] – rRheb + GDP <br />
**[[2gjs]] – hRad1 + GDP<br />
**[[3q72]], [[3q7p]], [[3q7q]] – hRad G-domain + GTP analog<br />
**[[2dpx]] – hRad GTPase domain<br />
**[[2gf0]] – hDiRas1 + GDP<br />
**[[2erx]] – hDiRas2 + Pi + GDP<br />
**[[3x1z]], [[3x1y]], [[3x1x]], [[3x1w]] – hRab-1B (mutant) + GPPNHP<br />
**[[1yu9]] - hRab-4A + GPPNHP<br />
**[[1yzq]] - hRab-6 + GNP<br />
**[[1x3s]] – hRab-18 + GPPNHP
**[[6huf]] - hRab-27A + GNP<br />
**[[2atx]] – hTc10 + GPPNHP<br />
**[[1g16]] – ySec4 + GDP<br />
**[[1g17]] - ySec4 + GIP<br />
*Ras-related small GTP-binding protein complex with protein
**[[3kuc]] – hRap-1A + proto oncogene Ser/Thr protein kinase<br />
**[[3cf6]] - hRap-1A + Rap guanine nucleotide exchange factor 4<br />
**[[3brw]] - hRap-1B + Rap GTPase-activating protein<br />
**[[4kvg]] – hRab-1A + RIAM<br />
**[[6ba6]] – hRab-1B + talin-1<br />
**[[4m8n]] – hRab-1B + plexin<br />
**[[4dxa]] – hRab-1B (mutant) + KRIT1<br />
**[[4hdq]], [[4hdo]] – hRab-1B + HEG1 + KRIT1<br />
**[[6axf]] – hRab-1B + Ras guanyl-releasing protein 2<br />
**[[5kho]] – hRab-1B + Ras-interacting protein 1<br />
**[[4mh0]], [[4mgz]], [[4mgy]], [[4mgk]], [[4mgi]] - hRap-1B + Rap guanine nucleotide exchange factor 4<br />
**[[1z0k]] – hRab-4 + rabenosyn-5<br />
**[[3tw8]] – hRab-1C + DENND<br />
**[[4ojk]] – hRab-11B + cGMP-dependent protein kinase 2<br />
**[[6ekk]] – hRab-35 + connecdenn + GDP<br />
**[[6if2]] – hRab-35 (mutant) + iporin + GTP<br />
**[[6if3]] – hRab-35 (mutant) + ACAP2 + GTP<br />
**[[6ces]] – hRag-C (mutant) + NPRL2 + NPRL3 + DEPDC5 + GNP – Cryo EM<br />
**[[6ehr]], [[5x6v]] – hRag-A + hRag-C + lamtor1 + lamtor2 + lamtor3 + lamtor4 + lamtor5<br />
*'''Interferon-induced GTP-binding protein'''
**[[3ljb]] – hMx1 stalk region<br />
**[[4p4u]] – hMx1 stalk region (mutant)<br />
**[[4p4t]] – hMx1 stalk region (mutant) + GDP<br />
**[[4p4s]] – hMx1 stalk region (mutant) + GMPPCP<br />
**[[3szr]] – hMx1 residues 33-662<br />
**[[5gtm]] – hMx1 residues 33-662 (mutant)<br />
**[[3zys]] – hMx1 + dynamin-1<br />
**[[4x0r]] – hMx2 stalk region (mutant)<br />
**[[4whj]] – hMx2 residues 84-715 (mutant)<br />
*'''Rho-related small GTP-binding protein'''
**[[2j1l]] – hRhoD
*Rho-related small GTP-binding protein complex with nucleotide
**[[2cls]] – hRho6 + GTP<br />
**[[2fv8]] - hRhoB + GDP<br />
**[[2gcn]] – hRhoC + GDP<br />
**[[2gco]] – hRhoC + GPPNHP<br />
**[[1z2c]] - hRhoC (mutant) + GMPPNP<br />
**[[2gcp]] – hRhoC + GSP<br />
**[[1m7b]] - hRhoE + GTP<br />
**[[1gwn]] - mRhoE + GTP <br />
**[[1a4r]] - hCdc42 (mutant) + GDP<br />
**[[1an0]] - hCdc42 + GDP<br />
**[[2qrz]] - hCdc42 + GCP<br />
*Rho-related small GTP-binding protein complex with protein
**[[2v55]] – hRhoE + Rho-associated protein kinase<br />
**[[3q3j]] – hRho6 + plexin-A2 nucleotide-binding domain<br />
**[[2rex]] – hRho6 + plexin-B1<br />
**[[1cc0]] – hRhoA + GDP-dissociation inhibitor + GDP<br />
**[[6bca]] - hRhoA + kinase anchor protein + GTP<br />
**[[3a58]] – yRho1 (mutant) + exocyst complex component Sec3 + cancidas<br />
**[[1gzs]] – Cdc42 + guanine nucleotide exchange factor – ''Salmonella typhimurium''<br />
**[[2kb0]] - hCdc42 (mutant)<br />
**[[1kz7]] - hCdc42 + guanine nucleotide exchange factor<br />
**[[1kzg]] - hCdc42 (mutant) + guanine nucleotide exchange factor (mutant)<br />
**[[2dfk]] – hCdc42 + collybistin II<br />
**[[2wm9]], [[2wmn]], [[2wmo]] - hCdc42 + DOCK9<br />
**[[3eg5]] - hCdc42 + protein diaphanous homolog 1 + GMPPNP<br />
**[[3gcg]] - hCdc42 + MAP<br />
**[[4ltr]] - hCdc42 + AMP-protein transferase<br />
**[[1nf3]] - hCdc42 + Par6<br />
**[[2ase]] - hCdc42 (mutant) - NMR<br />
**[[1ki1]] – hCdc42 + intersectin long form<br />
**[[1ees]] – hCdc42 + MapK3 peptide - NMR<br />
**[[1doa]] - hCdc42 + GDP-dissociation inhibitor<br />
**[[2ngr]] – hCdc42 + GTPase-activating protein C terminal + GDP<br />
**[[1am4]] – hCdc42 + GTPase-activating protein rhoGAP + GNP<br />
**[[1grn]] – hCdc42 + GTPase-activating protein rhoGAP + GDP<br />
**[[1cf4]] – hCdc42 (mutant) + ACK GTPase-binding domain + GNP - NMR<br />
**[[1cee]] – hCdc42 + WASP GTPase-binding domain + GCP - NMR<br />
**[[2odb]] – hCdc42 + PAK6 CRIB domain + GCP <br />
**[[3qbv]] – hCdc42 (mutant) + intersectin + GDP <br />
**[[4did]] – hCdc42 + inositol phosphate phosphatase + GDP <br />
**[[1cf4]] – hCdc42 (mutant) + dedicator of cytokinesis protein 8<br />
**[[4itr]] – hCdc42 + AMP-protein transferase + GDP + AMP<br />
*'''Rac-like GTP-binding protein'''
**[[4u5x]] – Arac1 (mutant) + GNPPNP – rice <br />
**[[2wbl]] – AtArac2 + Rho of plant guanine nucleotide exchange factor 8 – ''Arabidopsis thaliana''<br />
**[[3bwd]] – AtArac6<br />
**[[2nty]] – AtArac5 + prone8<br />
**[[2j0v]] – AtArac7 (mutant)<br />
*'''Rab-related small GTP-binding protein'''
**[[2ys8]] – hRabJ DNAJ domain – NMR<br />
*'''Flagella-associated GTP-binding protein'''
**[[2px0]] – BsFlhF + GMP-PNP <br />
**[[2px3]] – BsFlhF + GTP<br />
*'''Small GTP-binding protein'''
**[[5kh0]] – GBP – ''Thermotoga neapolitana''<br />
*'''Small GTP-binding protein ERA'''
**[[1ega]] – EcERA <br />
**[[3ieu]] – EcERA + GDP <br />
**[[3iev]] – AaERA + RNA + Mg-GNP <br />
**[[1x1l]] – TtERA + RNA – Cryo EM<br />
**[[1x18]] – TtERA + RNA + RPS2 + RPS7 + RPS11 + RPS18 – Cryo EM<br />
*'''Small GTP-binding protein Rheb'''
**[[1xtq]], [[5yxh]] – hRheb + GDP<br />
**[[1xts]] - hRheb + GTP<br />
**[[1xtr]] - hRheb + GPPNHP<br />
**[[3sea]] - hRheb + GDP + GNP<br />
**[[6bt0]], [[6bsx]] - hRheb + GDP + inhibitor<br />
**[[3t5g]] – hRheb + GMP-PDE delta<br />
**[[4o25]] – mRheb + GTP - mouse<br />
**[[4o2l]] - mRheb (mutant) + GTP <br />
**[[4o2r]] - mRheb (mutant) + GDP <br />
**[[3t5g]] – hRheB + GMP-PDE δ<br />
**[[2l0x]] – rRheb + GDP<br />
*'''Small GTP-binding protein Gem'''
**[[2cjw]], [[2ht6]], [[2g3y]] – hGem G domain + GDP<br />
*'''Small GTP-binding protein Ran'''
**[[2mmc]], [[2mmg]] – hRan <br />
*Ran binary complex
**[[3gj0]], [[5ciw]], [[5cit]], [[5ciq]] – hRan + GDP<br />
**[[5cj2]] – hRan (mutant) + GDP<br />
**[[1i2m]] – hRan + regulator of chromosome condensation 1<br />
**[[1byu]] – Ran + GDP - dog<br />
**[[1qg2]], [[1qg4]], [[3ran]] – dRan (mutant) + GDP<br />
**[[2bku]] – dRan + importin<br />
*Ran ternary complex
**[[1rrp]] – hRan + Nup358 + GTP analog<br />
**[[1qbk]] – hRan + karyopherin β2 + GTP analog<br />
**[[1ibr]] – hRan + importin β1 subunit + GTP analog<br />
**[[4ol0]] – hRan + importin 12 + GTP<br />
**[[3ea5]] – hRan (mutant) + importin β1 subunit + GDP <br />
**[[6q82]] – hRan (mutant) + importin β-like protein + GTP<br />
**[[4c0q]] - hRan (mutant) + importin 12 + GTP <br />
**[[3nc1]] – hRan (mutant) + exportin 1 + GTP <br />
**[[5clq]] – hRan (mutant) + RanBD1 + GNP <br />
**[[5cll]] – hRan + RanBD1 + GDP <br />
**[[3ch5]], [[3gj3]], [[3gj4]], [[3gj5]], [[3gj6]], [[3gj7]], [[3gj8]] – hRan + Nup153 + GDP<br />
**[[3w3z]] – dRan + importin β1 subunit + GTP <br />
**[[5bxq]] – dRan + NTF-2 + GDP <br />
*Ran larger complex
**[[3gjx]] – hRan + snurportin 1 + exportin 1 + GTP <br />
**[[3nby]], [[3nbz]], [[3nc0]] – hRan (mutant) + snurportin 1 + exportin 1 + GTP <br />
**[[1k5d]], [[5zpu]] – hRan + Ran-specific GTPase-activating protein + Ran GTPase activating protein 1 + GTP analog<br />
**[[1k5g]] – hRan + Ran-specific GTPase-activating protein + Ran GTPase activating protein 1 + GDP <br />
**[[4gpt]], [[4gmx]], [[4hat]], [[4hb2]], [[4hb3]] – hRan + Ran-specific GTPase-activating protein + exportin 1 + GNP <br />
**[[4hat]], [[4hau]], [[4hav]], [[4haw]], [[4hax]], [[4hay]], [[4haz]], [[4hb0]], [[4hb4]] – hRan + Ran-specific GTPase-activating protein + exportin 1 + GNP + antibiotic<br />
**[[5jlj]] – hRan + Ran-specific GTPase-activating protein + exportin 1 + GNP + inhibitor<br />
**[[4wvf]] – hRan + Ran-specific GTPase-activating protein + CRM1P + GNP + inhibitor<br />
**[[6cit]] – hRan + Ran-specific GTPase-activating protein + exportin + NS2<br />
**[[6a3e]], [[6a3c]], [[6a3b]], [[6a3a]], [[6a38]] – hRan + Ran-specific GTPase-activating protein + exportin + NES + GTP<br />
**[[5ytb]], [[5yst]], [[5yro]] – hRan (mutant) + Ran-specific GTPase-activating protein + exportin + GTP<br />
**[[5ysu]] – hRan (mutant) + Ran-specific GTPase-activating protein + exportin + GTP + plumbagin<br />
**[[5uww]], [[5uwu]], [[5uwt]], [[5uws]], [[5uwr]], [[5uwq]], [[5uwp]], [[5uwo]], [[5uwj]], [[5uwi]], [[5uwh]], [[5dif]], [[5di9]], [[5dhf]], [[5dha]], [[5dh9]] – hRan + Ran-specific GTPase-activating protein + exportin 1 + peptide<br />
**[[3zjy]] – hRan (mutant) + importin 13 + EIF-1A + GTP <br />
**[[6q84]] – hRan (mutant) + importin β-like protein + EIF-4D + GTP<br />
**[[5dlq]] – hRan (mutant) + exportin 4 + EIF-5A + GTP <br />
**[[5dis]] – hRan (mutant) + exportin 1 + RNA U transporter + Nup214 + GTP <br />
**[[3a6p]] – dRan + pre-microRNA + exportin 5 + peptide <br />
**[[3icq]] – yRan + RNA + exportin T  <br />
**[[3m1i]] – yRan + Ran-specific GTPase-activating protein + exportin 1 + GTP <br />
*'''Small GTPase h-Ras''' see [[GTPase HRas]]
*'''Heterotrimeric G protein see [[Transducin]]'''
}}
==See Also==
==See Also==
* [[G protein-coupled receptor]]
* [[G protein-coupled receptor]]
Retrieved from "https://proteopedia.org/GTP-binding_protein"