2yzs: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[2yzs]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZS OCA]. For a guided tour on the structure components use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2YZS FirstGlance].

<table><tr><td colspan='2'>[[2yzs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZS OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=2YZS FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2yzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzs OCA], [~~http~~://pdbe.org/2yzs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2yzs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2yzs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2yzs ProSAT], [~~http~~://www.topsan.org/Proteins/RSGI/2yzs TOPSAN]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=2yzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzs OCA], [https://pdbe.org/2yzs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yzs RCSB], [https://www.ebi.ac.uk/pdbsum/2yzs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yzs ProSAT], [https://www.topsan.org/Proteins/RSGI/2yzs TOPSAN]</td></tr>

</table>

== Function ==

[[~~http~~://www.uniprot.org/uniprot/CAS1_AQUAE CAS1_AQUAE]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.[HAMAP-Rule:MF_01470]

[[https://www.uniprot.org/uniprot/CAS1_AQUAE CAS1_AQUAE]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.[HAMAP-Rule:MF_01470]

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

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@@ Line 3: / Line 3: @@
 <StructureSection load='2yzs' size='340' side='right'caption='[[2yzs]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2yzs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YZS FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2yzs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YZS FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzs OCA], [http://pdbe.org/2yzs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yzs RCSB], [http://www.ebi.ac.uk/pdbsum/2yzs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yzs ProSAT], [http://www.topsan.org/Proteins/RSGI/2yzs TOPSAN]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzs OCA], [https://pdbe.org/2yzs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yzs RCSB], [https://www.ebi.ac.uk/pdbsum/2yzs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yzs ProSAT], [https://www.topsan.org/Proteins/RSGI/2yzs TOPSAN]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/CAS1_AQUAE CAS1_AQUAE]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.[HAMAP-Rule:MF_01470]
+[[https://www.uniprot.org/uniprot/CAS1_AQUAE CAS1_AQUAE]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.[HAMAP-Rule:MF_01470]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]