6kk7: Difference between revisions
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==Structure of thermal-stabilised(M6) human GLP-1 receptor transmembrane domain== | |||
<StructureSection load='6kk7' size='340' side='right'caption='[[6kk7]], [[Resolution|resolution]] 3.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6kk7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KK7 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=97Y:N-{4-[(R)-(3,3-DIMETHYLCYCLOBUTYL)({6-[4-(TRIFLUOROMETHYL)-1H-IMIDAZOL-1-YL]PYRIDIN-3-YL}AMINO)METHYL]BENZENE-1-CARBONYL}-BETA-ALANINE'>97Y</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vew|5vew]]</td></tr> | ||
[[Category: Song, G | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6kk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kk7 OCA], [http://pdbe.org/6kk7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kk7 RCSB], [http://www.ebi.ac.uk/pdbsum/6kk7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kk7 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/GLP1R_HUMAN GLP1R_HUMAN]] This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Song, G J]] | |||
[[Category: Allosteric modulator]] | |||
[[Category: Diabetes]] | |||
[[Category: Gpcr]] | |||
[[Category: Seven-transmembrane]] | |||
[[Category: Signaling protein]] | |||
Revision as of 11:01, 13 November 2019
Structure of thermal-stabilised(M6) human GLP-1 receptor transmembrane domain
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