5qts: Difference between revisions

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'''Unreleased structure'''


The entry 5qts is ON HOLD
==PanDDA analysis group deposition -- Crystal Structure of NUDT5 in complex with 8J-537S==
 
<StructureSection load='5qts' size='340' side='right'caption='[[5qts]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
Authors: Dubianok, Y., Krojer, T., Kovacs, H., Moriaud, F., Wright, N., Strain-Damerell, C., Burgess-Brown, N., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5qts]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QTS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QTS FirstGlance]. <br>
Description: PanDDA analysis group deposition --Crystal Structure of NUDT5 in complex with 8J-537S
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PWS:3-methyl-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidin-4(3H)-one'>PWS</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qts FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qts OCA], [http://pdbe.org/5qts PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qts RCSB], [http://www.ebi.ac.uk/pdbsum/5qts PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qts ProSAT]</span></td></tr>
[[Category: Moriaud, F]]
</table>
[[Category: Wright, N]]
== Function ==
[[Category: Arrowsmith, C.H]]
[[http://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN]] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Burgess-Brown, N]]
[[Category: Burgess-Brown, N]]
[[Category: Delft, F von]]
[[Category: Dubianok, Y]]
[[Category: Dubianok, Y]]
[[Category: Edwards, A]]
[[Category: Kovacs, H]]
[[Category: Kovacs, H]]
[[Category: Edwards, A]]
[[Category: Krojer, T]]
[[Category: Moriaud, F]]
[[Category: Strain-Damerell, C]]
[[Category: Strain-Damerell, C]]
[[Category: Krojer, T]]
[[Category: Wright, N]]
[[Category: Von Delft, F]]
[[Category: Hydrolase]]
[[Category: Bountra, C]]
[[Category: Pandda]]
[[Category: Sgc - diamond i04-1 fragment screening]]
[[Category: Xchemexplorer]]
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