6sid: Difference between revisions
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==Crystal structure of the C-lobe of drosophila Arc 1 at atomic resolution== | |||
<StructureSection load='6sid' size='340' side='right'caption='[[6sid]], [[Resolution|resolution]] 1.05Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6sid]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SID FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6sid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sid OCA], [http://pdbe.org/6sid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6sid RCSB], [http://www.ebi.ac.uk/pdbsum/6sid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6sid ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: Hallin, E | == Function == | ||
[[http://www.uniprot.org/uniprot/ARC1_DROME ARC1_DROME]] Master regulator of synaptic plasticity that self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer from motorneurons to muscles (PubMed:29328915). Arc1 protein is released from motorneurons in extracellular vesicles that mediate the transfer of Arc1 mRNA into muscle cells, where Arc1 mRNA can undergo activity-dependent translation (PubMed:29328915). Intercellular transfer od Arc1 mRNA is required for synaptic plasticity at the neuromuscular junction (PubMed:29328915). May play a role in energy balance: required for regulation of body fat by a specific population of brain neurons, named E347, that are necessary and sufficient for proper body fat storage (PubMed:26209258).<ref>PMID:26209258</ref> <ref>PMID:29328915</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Hallin, E I]] | |||
[[Category: Kursula, P]] | [[Category: Kursula, P]] | ||
[[Category: Arc]] | |||
[[Category: Atomic resolution]] | |||
[[Category: Capsid assembly]] | |||
[[Category: Gag homology]] | |||
[[Category: Virus like particle]] | |||
Revision as of 15:44, 28 August 2019
Crystal structure of the C-lobe of drosophila Arc 1 at atomic resolution
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