6qyn: Difference between revisions
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<StructureSection load='6qyn' size='340' side='right'caption='[[6qyn]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='6qyn' size='340' side='right'caption='[[6qyn]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6qyn]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6qyn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QYN FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JL8:(2~{R})-2-[5-(3-chloranyl-2-methyl-4-oxidanyl-phenyl)-6-ethyl-thieno[2,3-d]pyrimidin-4-yl]oxy-3-phenyl-propanoic+acid'>JL8</scene>, <scene name='pdbligand= | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=JL8:(2~{R})-2-[5-(3-chloranyl-2-methyl-4-oxidanyl-phenyl)-6-ethyl-thieno[2,3-d]pyrimidin-4-yl]oxy-3-phenyl-propanoic+acid'>JL8</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qyn OCA], [https://pdbe.org/6qyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qyn RCSB], [https://www.ebi.ac.uk/pdbsum/6qyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qyn ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/MCL1_HUMAN MCL1_HUMAN] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<ref>PMID:10766760</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 6qyn" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6qyn" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]] | |||
*[[Maltose-binding protein 3D structures|Maltose-binding protein 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Cauquil | [[Category: Cauquil N]] | ||
[[Category: Chen | [[Category: Chen I]] | ||
[[Category: Csekei | [[Category: Csekei M]] | ||
[[Category: Davidson | [[Category: Davidson J]] | ||
[[Category: Davis | [[Category: Davis B]] | ||
[[Category: Demarles | [[Category: Demarles D]] | ||
[[Category: Dokurno | [[Category: Dokurno P]] | ||
[[Category: Geneste | [[Category: Geneste O]] | ||
[[Category: Hubbard | [[Category: Hubbard RE]] | ||
[[Category: Kotschy | [[Category: Kotschy A]] | ||
[[Category: LeToumelin-Braizat | [[Category: LeToumelin-Braizat G]] | ||
[[Category: Murray | [[Category: Murray J]] | ||
[[Category: Ondi | [[Category: Ondi L]] | ||
[[Category: Paczal | [[Category: Paczal A]] | ||
[[Category: Pedder | [[Category: Pedder C]] | ||
[[Category: Perron-Sierra | [[Category: Perron-Sierra F]] | ||
[[Category: Radics | [[Category: Radics G]] | ||
[[Category: Robertson | [[Category: Robertson A]] | ||
[[Category: Smith | [[Category: Smith J]] | ||
[[Category: Surgenor | [[Category: Surgenor AE]] | ||
[[Category: Szabo | [[Category: Szabo ZB]] | ||
[[Category: Szlavik | [[Category: Szlavik Z]] | ||
[[Category: Zarka | [[Category: Zarka M]] | ||