Hyaluronidase: Difference between revisions
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== Function == | == Function == | ||
'''Hyaluronidase''' (HU) hydrolyzes complex carbohydrates such as hyaluronan which is part of the extracellular matrix. The hydrolysis increases tissue permeability<ref>PMID:17503783</ref>. | '''Hyaluronidase''' or '''hyaluronate lyase''' (HU) hydrolyzes complex carbohydrates such as hyaluronan which is part of the extracellular matrix. The hydrolysis increases tissue permeability<ref>PMID:17503783</ref>. | ||
[[Image:hya_xdt_100906.jpeg|left|thumb|'''Superposition of the EGF-like domain of hyaluronidase-1 (yellow) and the heparin-binding EGF-like growth factor (light blue)'''. The three disulphide bonds of the EGF domains (highlighted red) exhibit the same pattern in the primary structure and are located in similar positions in the 3D structure. |400px]] | [[Image:hya_xdt_100906.jpeg|left|thumb|'''Superposition of the EGF-like domain of hyaluronidase-1 (yellow) and the heparin-binding EGF-like growth factor (light blue)'''. The three disulphide bonds of the EGF domains (highlighted red) exhibit the same pattern in the primary structure and are located in similar positions in the 3D structure. |400px]] | ||
