6kp6: Difference between revisions
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The | ==The structural study of mutation induced inactivation of Human muscarinic receptor M4== | ||
<StructureSection load='6kp6' size='340' side='right'caption='[[6kp6]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6kp6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KP6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KP6 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6kp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kp6 OCA], [http://pdbe.org/6kp6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kp6 RCSB], [http://www.ebi.ac.uk/pdbsum/6kp6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kp6 ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: Wu, L | == Function == | ||
[[http://www.uniprot.org/uniprot/ACM4_HUMAN ACM4_HUMAN]] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Hua, T]] | |||
[[Category: Liu, Z J]] | |||
[[Category: Wang, J J]] | |||
[[Category: Wu, L J]] | |||
[[Category: Wu, M]] | [[Category: Wu, M]] | ||
[[Category: | [[Category: G protein-coupled receptor]] | ||
[[Category: | [[Category: Ligand screening]] | ||
[[Category: | [[Category: M4]] | ||
[[Category: Membrane protein]] | |||
[[Category: Muscarinic acetylcholine receptor]] | |||
[[Category: Mutation design]] | |||
Revision as of 07:18, 11 March 2020
The structural study of mutation induced inactivation of Human muscarinic receptor M4
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