6slh: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6slh is ~~ON HOLD~~

==Conformational flexibility within the small domain of human serine racemase.==

~~Authors~~: ~~Koulouris~~, C.R., ~~Bax~~, B., ~~Atack, J~~., ~~Roe, S~~.M.

== Structural highlights ==

<table><tr><td colspan='2'>[[6slh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SLH OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SLH FirstGlance].

~~Description~~: ~~Conformational flexibility within~~ the ~~small domain~~ of ~~human~~ serine ~~racemase~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>

[[Category: ~~Roe~~, ~~S.M~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6slh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6slh OCA], [http://pdbe.org/6slh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6slh RCSB], [http://www.ebi.ac.uk/pdbsum/6slh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6slh ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/SRR_HUMAN SRR_HUMAN]] Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.<ref>PMID:11054547</ref> <ref>PMID:20106978</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Atack, J]]

[[Category: Bax, B]]

[[Category: Koulouris, C.R]]

[[Category: Koulouris, C R]]

[[Category: ~~Atack~~, J]]

[[Category: Roe, S M]]

[[Category: D-serine]]

[[Category: Isomerase]]

[[Category: Nmda receptor]]

[[Category: Plp-dependent]]

[[Category: Racemization]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6slh is ON HOLD
+==Conformational flexibility within the small domain of human serine racemase.==
+<StructureSection load='6slh' size='340' side='right'caption='[[6slh]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
-Authors: Koulouris, C.R., Bax, B., Atack, J., Roe, S.M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6slh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SLH FirstGlance]. <br>
-Description: Conformational flexibility within the small domain of human serine racemase.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
-[[Category: Roe, S.M]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6slh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6slh OCA], [http://pdbe.org/6slh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6slh RCSB], [http://www.ebi.ac.uk/pdbsum/6slh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6slh ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/SRR_HUMAN SRR_HUMAN]] Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.<ref>PMID:11054547</ref> <ref>PMID:20106978</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Atack, J]]
 [[Category: Bax, B]]
-[[Category: Koulouris, C.R]]
+[[Category: Koulouris, C R]]
-[[Category: Atack, J]]
+[[Category: Roe, S M]]
+[[Category: D-serine]]
+[[Category: Isomerase]]
+[[Category: Nmda receptor]]
+[[Category: Plp-dependent]]
+[[Category: Racemization]]