6r3l: Difference between revisions

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<StructureSection load='6r3l' size='340' side='right'caption='[[6r3l]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
<StructureSection load='6r3l' size='340' side='right'caption='[[6r3l]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6r3l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R3L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6R3L FirstGlance]. <br>
<table><tr><td colspan='2'>[[6r3l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_niger Aspergillus niger]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R3L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6R3L FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BYN:hydroxylated+prenyl-FMN'>BYN</scene>, <scene name='pdbligand=JSH:prFMN+cofactor+and+cinnamic+acid+adduct'>JSH</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SYN:ETHENYLBENZENE'>SYN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.24&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenacrylate_decarboxylase Phenacrylate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.102 4.1.1.102] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BYN:hydroxylated+prenyl-FMN'>BYN</scene>, <scene name='pdbligand=JSH:prFMN+cofactor+and+cinnamic+acid+adduct'>JSH</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SYN:ETHENYLBENZENE'>SYN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6r3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r3l OCA], [http://pdbe.org/6r3l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r3l RCSB], [http://www.ebi.ac.uk/pdbsum/6r3l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r3l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6r3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r3l OCA], [https://pdbe.org/6r3l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6r3l RCSB], [https://www.ebi.ac.uk/pdbsum/6r3l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6r3l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FDC1_ASPNC FDC1_ASPNC]] Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.[HAMAP-Rule:MF_03196]<ref>PMID:26083754</ref>
[https://www.uniprot.org/uniprot/FDC1_ASPNC FDC1_ASPNC] Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.[HAMAP-Rule:MF_03196]<ref>PMID:26083754</ref>  
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aspergillus niger]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Phenacrylate decarboxylase]]
[[Category: Bailey SS]]
[[Category: Bailey, S S]]
[[Category: Leys D]]
[[Category: Leys, D]]
[[Category: Lyase]]
[[Category: Prfmn binding]]
[[Category: Ubid]]

Latest revision as of 12:14, 24 January 2024

Aspergillus niger ferulic acid decarboxylase (Fdc) in complex with the covalent adduct formed between prFMN cofactor and cinnamic acid following decarboxylation (Int3)

6r3l, resolution 1.24Å

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