Sandbox GGC9: Difference between revisions
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== Background == | == Background == | ||
The androgen receptor (AR) is a member of the nuclear receptor superfamily of ligand-activated transcription factors. Androgen activation of AR regulates prostate growth, bone, muscle mass, and spermatogenesis. | The androgen receptor (AR) is a member of the nuclear receptor superfamily of ligand-activated transcription factors. Androgen activation of AR regulates prostate growth, bone, muscle mass, and spermatogenesis. | ||
== ligands == | == ligands == | ||
The ligands that have a high affinity to the AR are Testosterone (T) and Dihydrotestosterone (DHT) | The ligands that have a high affinity to the AR are Testosterone (T) and Dihydrotestosterone (DHT). Testosterone is a cholesterol derivative, this hormone helps facilitate male maturation and development. | ||
== Relevance == | == Relevance == | ||
