6knz: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6knz is ~~ON HOLD until Paper Publication~~

==Crystal structure of T2R-TTL-KXO1 complex==

~~Authors~~: ~~Chen~~, Q., Yu, Y.

== Structural highlights ==

<table><tr><td colspan='2'>[[6knz]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KNZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KNZ FirstGlance]. <br>

~~Description~~: ~~Crystal structure~~ of ~~T2R~~-~~TTL~~-~~KXO1 complex~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DN0:2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]-~{N}-(phenylmethyl)ethanamide'>DN0</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6knz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6knz OCA], [http://pdbe.org/6knz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6knz RCSB], [http://www.ebi.ac.uk/pdbsum/6knz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6knz ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref> [[http://www.uniprot.org/uniprot/TBB2B_BOVIN TBB2B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).

== References ==

__TOC__

</StructureSection>

[[Category: Bos taurus]]

[[Category: Large Structures]]

[[Category: Chen, Q]]

[[Category: Yu, Y]]

[[Category: ~~Chen, Q~~]]

[[Category: Complex]]

[[Category: Inhibitor]]

[[Category: Structural protein]]

[[Category: Tubulin]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6knz is ON HOLD  until Paper Publication
+==Crystal structure of T2R-TTL-KXO1 complex==
+<StructureSection load='6knz' size='340' side='right'caption='[[6knz]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
-Authors: Chen, Q., Yu, Y.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6knz]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KNZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KNZ FirstGlance]. <br>
-Description: Crystal structure of T2R-TTL-KXO1 complex
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DN0:2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]-~{N}-(phenylmethyl)ethanamide'>DN0</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6knz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6knz OCA], [http://pdbe.org/6knz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6knz RCSB], [http://www.ebi.ac.uk/pdbsum/6knz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6knz ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref>  [[http://www.uniprot.org/uniprot/TBB2B_BOVIN TBB2B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Bos taurus]]
+[[Category: Large Structures]]
+[[Category: Chen, Q]]
 [[Category: Yu, Y]]
-[[Category: Chen, Q]]
+[[Category: Complex]]
+[[Category: Inhibitor]]
+[[Category: Structural protein]]
+[[Category: Tubulin]]