6kr2: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6kr2 is ~~ON HOLD until Paper Publication~~

==Crystal structure of Dengue virus nonstructural protein NS5 (form 1)==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6kr2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KR2 FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6kr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kr2 OCA], [http://pdbe.org/6kr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kr2 RCSB], [http://www.ebi.ac.uk/pdbsum/6kr2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kr2 ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/Q91H74_9FLAV Q91H74_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Gong, P]]

[[Category: Lu, G]]

[[Category: Wu, J]]

[[Category: Ye, H Q]]

[[Category: Methyltransferase]]

[[Category: Polymerase]]

[[Category: Viral protein]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6kr2 is ON HOLD  until Paper Publication
+==Crystal structure of Dengue virus nonstructural protein NS5 (form 1)==
+<StructureSection load='6kr2' size='340' side='right'caption='[[6kr2]], [[Resolution|resolution]] 3.06&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6kr2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KR2 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6kr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kr2 OCA], [http://pdbe.org/6kr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kr2 RCSB], [http://www.ebi.ac.uk/pdbsum/6kr2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kr2 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/Q91H74_9FLAV Q91H74_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Gong, P]]
+[[Category: Lu, G]]
+[[Category: Wu, J]]
+[[Category: Ye, H Q]]
+[[Category: Methyltransferase]]
+[[Category: Polymerase]]
+[[Category: Viral protein]]