6nju: Difference between revisions
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==Mouse endonuclease G mutant H97A bound to A-DNA== | |||
<StructureSection load='6nju' size='340' side='right'caption='[[6nju]], [[Resolution|resolution]] 2.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6nju]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NJU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NJU FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nju OCA], [http://pdbe.org/6nju PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nju RCSB], [http://www.ebi.ac.uk/pdbsum/6nju PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nju ProSAT]</span></td></tr> | ||
[[Category: Ho, | </table> | ||
[[Category: | == Function == | ||
[[Category: Robertson, A | [[http://www.uniprot.org/uniprot/NUCG_MOUSE NUCG_MOUSE]] Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity). | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Czarny, R S]] | |||
[[Category: Ho, E N]] | |||
[[Category: Ho, P S]] | |||
[[Category: Robertson, A B]] | |||
[[Category: Zanden, C M.Vander]] | |||
[[Category: Complex]] | |||
[[Category: Endonuclease]] | |||
[[Category: Recombination]] | |||
Revision as of 07:34, 8 January 2020
Mouse endonuclease G mutant H97A bound to A-DNA
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