6stz: Difference between revisions
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==Crystal structure of dimethylated RSLex - cucurbituril free form== | |||
<StructureSection load='6stz' size='340' side='right'caption='[[6stz]], [[Resolution|resolution]] 1.14Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6stz]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6STZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6STZ FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BDF:BETA-D-FRUCTOPYRANOSE'>BDF</scene></td></tr> | |||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6stz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6stz OCA], [http://pdbe.org/6stz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6stz RCSB], [http://www.ebi.ac.uk/pdbsum/6stz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6stz ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
A crystalline biohybrid with a 4 : 1 protein : cucurbituril mass ratio is presented. This result was achieved by engineering additional cucurbit[7]uril (Q7) binding sites into a beta-propeller protein. In contrast to the parent protein, Q7-controlled assembly of the engineered variant occurred in solution, as evidenced by NMR and SAXS measurements. | |||
Engineered assembly of a protein-cucurbituril biohybrid.,Guagnini F, Engilberge S, Ramberg KO, Perez J, Crowley PB Chem Commun (Camb). 2020 Jan 2;56(3):360-363. doi: 10.1039/c9cc07198a. PMID:31825399<ref>PMID:31825399</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
[[Category: Crowley, P | <div class="pdbe-citations 6stz" style="background-color:#fffaf0;"></div> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Crowley, P B]] | |||
[[Category: Engilberge, S]] | |||
[[Category: Guagnini, F]] | [[Category: Guagnini, F]] | ||
[[Category: | [[Category: Crystal engineering]] | ||
[[Category: Cucurbituril]] | |||
[[Category: Molecular glue]] | |||
[[Category: Sugar binding protein]] | |||
Revision as of 06:34, 19 February 2020
Crystal structure of dimethylated RSLex - cucurbituril free form
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