6uc0: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6uc0 is ~~ON HOLD~~

==Isolated S3D-cofilin bound to an actin filament==

~~Authors~~: ~~Huehn~~, A.R., ~~Bibeau, J~~.P., ~~Schramm~~, A.C., ~~Cao, W~~.~~, De La Cruz, E~~.M., ~~Sindelar, C~~.V.

== Structural highlights ==

<table><tr><td colspan='2'>[[6uc0]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UC0 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UC0 FirstGlance].

~~Description~~: ~~Isolated S3D~~-~~cofilin bound to an~~ actin ~~filament~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

[[Category: ~~Schramm~~, ~~A.C~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uc0 OCA], [http://pdbe.org/6uc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uc0 RCSB], [http://www.ebi.ac.uk/pdbsum/6uc0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uc0 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [[http://www.uniprot.org/uniprot/COF1_HUMAN COF1_HUMAN]] Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:15580268</ref> <ref>PMID:21834987</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Oryctolagus cuniculus]]

[[Category: Bibeau, J P]]

[[Category: Cao, W]]

[[Category: ~~Sindelar~~, C.V]]

[[Category: Cruz, E M.De La]]

[[Category: ~~De La Cruz~~, ~~E.M~~]]

[[Category: Huehn, A R]]

[[Category: ~~Huehn~~, A.R]]

[[Category: Schramm, A C]]

[[Category: ~~Bibeau~~, ~~J.P~~]]

[[Category: Sindelar, C V]]

[[Category: Cytoskeleton]]

[[Category: Structural protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6uc0 is ON HOLD
+==Isolated S3D-cofilin bound to an actin filament==
+<StructureSection load='6uc0' size='340' side='right'caption='[[6uc0]], [[Resolution|resolution]] 7.50&Aring;' scene=''>
-Authors: Huehn, A.R., Bibeau, J.P., Schramm, A.C., Cao, W., De La Cruz, E.M., Sindelar, C.V.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6uc0]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UC0 FirstGlance]. <br>
-Description: Isolated S3D-cofilin bound to an actin filament
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6vao|6vao]], [[6vau|6vau]], [[6uby|6uby]], [[6uc4|6uc4]]</td></tr>
-[[Category: Schramm, A.C]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uc0 OCA], [http://pdbe.org/6uc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uc0 RCSB], [http://www.ebi.ac.uk/pdbsum/6uc0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uc0 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [[http://www.uniprot.org/uniprot/COF1_HUMAN COF1_HUMAN]] Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:15580268</ref> <ref>PMID:21834987</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Oryctolagus cuniculus]]
+[[Category: Bibeau, J P]]
 [[Category: Cao, W]]
-[[Category: Sindelar, C.V]]
+[[Category: Cruz, E M.De La]]
-[[Category: De La Cruz, E.M]]
+[[Category: Huehn, A R]]
-[[Category: Huehn, A.R]]
+[[Category: Schramm, A C]]
-[[Category: Bibeau, J.P]]
+[[Category: Sindelar, C V]]
+[[Category: Cytoskeleton]]
+[[Category: Structural protein]]