6ucc: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6ucc ~~is ON HOLD~~

==Structure of human PACRG-MEIG1 complex (limited proteolysis)==

~~Authors~~: ~~Khan, N~~., ~~Croteau~~, N., ~~Pelletier~~, D., ~~Veyron~~, S., ~~Trempe, J~~.F.

== Structural highlights ==

<table><tr><td colspan='2'>[[6ucc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UCC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UCC FirstGlance]. <br>

~~Description~~: ~~Structure~~ of ~~human PACRG~~-~~MEIG1 complex (limited proteolysis~~)

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ucc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ucc OCA], [http://pdbe.org/6ucc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ucc RCSB], [http://www.ebi.ac.uk/pdbsum/6ucc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ucc ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/PACRG_HUMAN PACRG_HUMAN]] Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease.<ref>PMID:14532270</ref> [[http://www.uniprot.org/uniprot/MEIG1_HUMAN MEIG1_HUMAN]] Essential for spermiogenesis.

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Croteau, N]]

[[Category: Khan, N]]

[[Category: Pelletier, D]]

[[Category: Trempe, J F]]

[[Category: Veyron, S]]

[[Category: ~~Trempe, J.F~~]]

[[Category: Axoneme]]

[[Category: ~~Pelletier, D~~]]

[[Category: Flagella]]

[[Category: ~~Khan, N~~]]

[[Category: Microtubule]]

[[Category: ~~Croteau, N~~]]

[[Category: Primary cilia]]

[[Category: Structural protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6ucc is ON HOLD
+==Structure of human PACRG-MEIG1 complex (limited proteolysis)==
+<StructureSection load='6ucc' size='340' side='right'caption='[[6ucc]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-Authors: Khan, N., Croteau, N., Pelletier, D., Veyron, S., Trempe, J.F.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ucc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UCC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UCC FirstGlance]. <br>
-Description: Structure of human PACRG-MEIG1 complex (limited proteolysis)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ucc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ucc OCA], [http://pdbe.org/6ucc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ucc RCSB], [http://www.ebi.ac.uk/pdbsum/6ucc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ucc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/PACRG_HUMAN PACRG_HUMAN]] Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease.<ref>PMID:14532270</ref>  [[http://www.uniprot.org/uniprot/MEIG1_HUMAN MEIG1_HUMAN]] Essential for spermiogenesis.
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Croteau, N]]
+[[Category: Khan, N]]
+[[Category: Pelletier, D]]
+[[Category: Trempe, J F]]
 [[Category: Veyron, S]]
-[[Category: Trempe, J.F]]
+[[Category: Axoneme]]
-[[Category: Pelletier, D]]
+[[Category: Flagella]]
-[[Category: Khan, N]]
+[[Category: Microtubule]]
-[[Category: Croteau, N]]
+[[Category: Primary cilia]]
+[[Category: Structural protein]]